Biomaterial Database

Serotonin: two different inhibitory actions on snail neurons. 1971

H M Gerschenfeld

Serotonin (5-hydroxytryptamine) inhibits snail neurons through two different mechanisms. Whereas on some cells it increases selectively the membrane permeability to chloride ions thus giving rise to a net influx of this ion, on other neurons it increases the permeability to potassium ions causing a net potassium efflux. The serotonin receptors involved in these two inhibitions are different; they also differ from the receptors involved in the excitatory action of serotonin previously described in snail neurons.

UI	MeSH Term	Description	Entries
D002463	Cell Membrane Permeability	A quality of cell membranes which permits the passage of solvents and solutes into and out of cells.	Permeability, Cell Membrane
D002712	Chlorides	Inorganic compounds derived from hydrochloric acid that contain the Cl- ion.	Chloride,Chloride Ion Level,Ion Level, Chloride,Level, Chloride Ion
D003864	Depression, Chemical	The decrease in a measurable parameter of a PHYSIOLOGICAL PROCESS, including cellular, microbial, and plant; immunological, cardiovascular, respiratory, reproductive, urinary, digestive, neural, musculoskeletal, ocular, and skin physiological processes; or METABOLIC PROCESS, including enzymatic and other pharmacological processes, by a drug or other chemical.	Chemical Depression,Chemical Depressions,Depressions, Chemical
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia