-transparent.png){kind=logo}
The 11-hydroxy metabolites of Delta(8).- and Delta(9)-tetrahydrocannabinol are more active than the parent compounds when administered to mice by either the intravenous or intracerebral route. Both Delta(8)- and Delta(9)-tetrahydrocannabinol are rapidly and extensively metabolized by the liver and not by the brain. The hypothesis that the 11-hydroxy metabolites may be the active form of tetrahydrocannabinol is discussed
Related Publications
H D Christensen, and
R I Freudenthal, and
J T Gidley, and
R Rosenfeld, and
G Boegli, and
L Testino, and
D R Brine, and
C G Pitt, and
M E Wall
March 1976,
The Journal of pharmacology and experimental therapeutics,
H D Christensen, and
R I Freudenthal, and
J T Gidley, and
R Rosenfeld, and
G Boegli, and
L Testino, and
D R Brine, and
C G Pitt, and
M E Wall
January 1970,
The Journal of clinical pharmacology and the journal of new drugs,
H D Christensen, and
R I Freudenthal, and
J T Gidley, and
R Rosenfeld, and
G Boegli, and
L Testino, and
D R Brine, and
C G Pitt, and
M E Wall
June 1977,
Biomedical mass spectrometry,
H D Christensen, and
R I Freudenthal, and
J T Gidley, and
R Rosenfeld, and
G Boegli, and
L Testino, and
D R Brine, and
C G Pitt, and
M E Wall
March 2007,
British journal of pharmacology,
H D Christensen, and
R I Freudenthal, and
J T Gidley, and
R Rosenfeld, and
G Boegli, and
L Testino, and
D R Brine, and
C G Pitt, and
M E Wall
December 1980,
Journal of pharmacobio-dynamics,
H D Christensen, and
R I Freudenthal, and
J T Gidley, and
R Rosenfeld, and
G Boegli, and
L Testino, and
D R Brine, and
C G Pitt, and
M E Wall
May 1976,
Psychopharmacology,
H D Christensen, and
R I Freudenthal, and
J T Gidley, and
R Rosenfeld, and
G Boegli, and
L Testino, and
D R Brine, and
C G Pitt, and
M E Wall
May 1976,
Psychopharmacology,
H D Christensen, and
R I Freudenthal, and
J T Gidley, and
R Rosenfeld, and
G Boegli, and
L Testino, and
D R Brine, and
C G Pitt, and
M E Wall
January 1976,
Antonie van Leeuwenhoek,
H D Christensen, and
R I Freudenthal, and
J T Gidley, and
R Rosenfeld, and
G Boegli, and
L Testino, and
D R Brine, and
C G Pitt, and
M E Wall
March 1978,
Toxicology and applied pharmacology,
H D Christensen, and
R I Freudenthal, and
J T Gidley, and
R Rosenfeld, and
G Boegli, and
L Testino, and
D R Brine, and
C G Pitt, and
M E Wall
March 1969,
Science (New York, N.Y.),
