Iron metabolism in patients undergoing regular dialysis therapy. 1971

B Brozovich, and W R Cattell, and M F Cottrall, and M M Gwyther, and J M McMillan, and J S Malpas, and A Salsbury, and N G Trott

Thirteen patients with chronic renal failure maintained on regular renal dialysis were studied. Seven proved to have iron deficiency on the basis of marrow iron studies, reticulocyte iron uptake, and saturation of the serum iron-binding capacity. They absorbed iron when given it by mouth and were able to utilize it for haemoglobin formation. Iron-deficient patients given 600 mg of ferrous sulphate daily for three months showed an increase in haemoglobin, but the failure to replace stores of iron is probably related to their relatively limited ability to absorb iron and the variable but sometimes considerable blood loss occurring with each dialysis.The loss may be occult, and prolonged iron therapy may be required. This is most safely achieved by giving iron by mouth.

UI MeSH Term Description Entries
D007501 Iron A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. Iron-56,Iron 56
D007503 Iron Isotopes Stable iron atoms that have the same atomic number as the element iron, but differ in atomic weight. Fe-54, 57, and 58 are stable iron isotopes. Isotopes, Iron
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011485 Protein Binding The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments. Plasma Protein Binding Capacity,Binding, Protein
D001798 Blood Proteins Proteins that are present in blood serum, including SERUM ALBUMIN; BLOOD COAGULATION FACTORS; and many other types of proteins. Blood Protein,Plasma Protein,Plasma Proteins,Serum Protein,Serum Proteins,Protein, Blood,Protein, Plasma,Protein, Serum,Proteins, Blood,Proteins, Plasma,Proteins, Serum
D001853 Bone Marrow The soft tissue filling the cavities of bones. Bone marrow exists in two types, yellow and red. Yellow marrow is found in the large cavities of large bones and consists mostly of fat cells and a few primitive blood cells. Red marrow is a hematopoietic tissue and is the site of production of erythrocytes and granular leukocytes. Bone marrow is made up of a framework of connective tissue containing branching fibers with the frame being filled with marrow cells. Marrow,Red Marrow,Yellow Marrow,Marrow, Bone,Marrow, Red,Marrow, Yellow
D005260 Female Females
D006400 Hematocrit The volume of packed RED BLOOD CELLS in a blood specimen. The volume is measured by centrifugation in a tube with graduated markings, or with automated blood cell counters. It is an indicator of erythrocyte status in disease. For example, ANEMIA shows a low value; POLYCYTHEMIA, a high value. Erythrocyte Volume, Packed,Packed Red-Cell Volume,Erythrocyte Volumes, Packed,Hematocrits,Packed Erythrocyte Volume,Packed Erythrocyte Volumes,Packed Red Cell Volume,Packed Red-Cell Volumes,Red-Cell Volume, Packed,Red-Cell Volumes, Packed,Volume, Packed Erythrocyte,Volume, Packed Red-Cell,Volumes, Packed Erythrocyte,Volumes, Packed Red-Cell
D006435 Renal Dialysis Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION. Dialysis, Extracorporeal,Dialysis, Renal,Extracorporeal Dialysis,Hemodialysis,Dialyses, Extracorporeal,Dialyses, Renal,Extracorporeal Dialyses,Hemodialyses,Renal Dialyses

Related Publications

B Brozovich, and W R Cattell, and M F Cottrall, and M M Gwyther, and J M McMillan, and J S Malpas, and A Salsbury, and N G Trott
December 1980, Danish medical bulletin,
B Brozovich, and W R Cattell, and M F Cottrall, and M M Gwyther, and J M McMillan, and J S Malpas, and A Salsbury, and N G Trott
January 1981, Nephron,
B Brozovich, and W R Cattell, and M F Cottrall, and M M Gwyther, and J M McMillan, and J S Malpas, and A Salsbury, and N G Trott
October 1973, Klinische Wochenschrift,
B Brozovich, and W R Cattell, and M F Cottrall, and M M Gwyther, and J M McMillan, and J S Malpas, and A Salsbury, and N G Trott
October 1971, Clinical science,
B Brozovich, and W R Cattell, and M F Cottrall, and M M Gwyther, and J M McMillan, and J S Malpas, and A Salsbury, and N G Trott
July 1982, Scottish medical journal,
B Brozovich, and W R Cattell, and M F Cottrall, and M M Gwyther, and J M McMillan, and J S Malpas, and A Salsbury, and N G Trott
January 1979, La Ricerca in clinica e in laboratorio,
B Brozovich, and W R Cattell, and M F Cottrall, and M M Gwyther, and J M McMillan, and J S Malpas, and A Salsbury, and N G Trott
February 1986, Vnitrni lekarstvi,
B Brozovich, and W R Cattell, and M F Cottrall, and M M Gwyther, and J M McMillan, and J S Malpas, and A Salsbury, and N G Trott
January 1972, Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association,
B Brozovich, and W R Cattell, and M F Cottrall, and M M Gwyther, and J M McMillan, and J S Malpas, and A Salsbury, and N G Trott
September 1978, The International journal of artificial organs,
B Brozovich, and W R Cattell, and M F Cottrall, and M M Gwyther, and J M McMillan, and J S Malpas, and A Salsbury, and N G Trott
August 1971, Clinical science,
Copied contents to your clipboard!