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In a survey of 246 soft tissue sarcomas in the extremities and limb girdles reported to the Finnish Cancer Registry in 1960-1969, two clear cell sarcomas of tendons and aponeurones were diagnosed. We subsequently diagnosed two more examples. Three tumors were located in the foot and one in the wrist. The histology of the tumors was characteristic, and three of them were shown to contain brown pigment tinctorially indistinguishable from melanin. The pigment could be bleached with potassium permanganate. Ultrastructural studies performed in the most recent case revealed premelanosomes in the cytoplasm of tumor cells. Increasing evidence in the literature and results of the present study seem to suggest that clear cell sarcoma of tendons and aponeuroses represents a soft tissue malignant melanoma.
T O Ekfors, and
V Rantakokko
September 1989,
Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association,
T O Ekfors, and
V Rantakokko
January 1990,
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie,
T O Ekfors, and
V Rantakokko
March 1991,
Cancer genetics and cytogenetics,
T O Ekfors, and
V Rantakokko
March 1987,
Clinical orthopaedics and related research,
T O Ekfors, and
V Rantakokko
January 1977,
Acta orthopaedica Scandinavica,
T O Ekfors, and
V Rantakokko
September 2005,
Skeletal radiology,
T O Ekfors, and
V Rantakokko
April 1970,
Cancer,
T O Ekfors, and
V Rantakokko
April 1978,
Oral surgery, oral medicine, and oral pathology,
T O Ekfors, and
V Rantakokko
January 1973,
Arkhiv patologii,
T O Ekfors, and
V Rantakokko
March 1993,
Histopathology,
