Paternal effects on the development of social behavior in Mus musculus. 1977

M L Smith, and E C Simmel

In order to extend the determination and description of effects of the father's phenotype on the development of social behavior in male mice, we tested 24 males from each of 2 highly inbred strains of Mus musculus, A/J and C57BL/6J. Approximately 1 week before the birth of the subjects, we replaced natural fathers with a foster parent such that, within each strain, 8 subjects had preweaning experience with same-strain males, 8 with other-strain males, and 8 with same-strain females, in addition to their natural mothers. Observations of social behavior were conducted at 21, 50, and 60 days of age. The results showed effects of the foster parent's phenotype on the development of social exploration in both strains and, possibly, on agonistic behavior in C57BL/6J mice. The different effects in the 2 strains indicate mechanisms dependent on genotype.

UI MeSH Term Description Entries
D008297 Male Males
D008805 Mice, Inbred A An inbred strain of mouse that is widely used in IMMUNOLOGY studies and cancer research. Mouse, Inbred A,Inbred A Mice,Inbred A Mouse
D008810 Mice, Inbred C57BL One of the first INBRED MOUSE STRAINS to be sequenced. This strain is commonly used as genetic background for transgenic mouse models. Refractory to many tumors, this strain is also preferred model for studying role of genetic variations in development of diseases. Mice, C57BL,Mouse, C57BL,Mouse, Inbred C57BL,C57BL Mice,C57BL Mice, Inbred,C57BL Mouse,C57BL Mouse, Inbred,Inbred C57BL Mice,Inbred C57BL Mouse
D010332 Paternal Behavior The behavior patterns associated with or characteristic of a father. Behavior, Paternal,Behaviors, Paternal,Paternal Behaviors
D010641 Phenotype The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment. Phenotypes
D001835 Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. Body Weights,Weight, Body,Weights, Body
D002755 Choice Behavior The act of making a selection among two or more alternatives, usually after a period of deliberation. Approach Behavior,Approach Behaviors,Behavior, Approach,Behavior, Choice,Behaviors, Approach,Behaviors, Choice,Choice Behaviors
D005106 Exploratory Behavior The tendency to explore or investigate a novel environment. It is considered a motivation not clearly distinguishable from curiosity. Curiosity,Novelty-Seeking Behavior,Behavior, Exploratory,Behavior, Novelty-Seeking,Behaviors, Exploratory,Behaviors, Novelty-Seeking,Curiosities,Exploratory Behaviors,Novelty Seeking Behavior,Novelty-Seeking Behaviors
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

M L Smith, and E C Simmel
July 1983, Physiology & behavior,
M L Smith, and E C Simmel
June 1988, Journal of comparative psychology (Washington, D.C. : 1983),
M L Smith, and E C Simmel
September 1989, Behavioral and neural biology,
M L Smith, and E C Simmel
December 1974, Behavior genetics,
M L Smith, and E C Simmel
May 1978, Developmental psychobiology,
M L Smith, and E C Simmel
June 2000, Journal of comparative psychology (Washington, D.C. : 1983),
M L Smith, and E C Simmel
May 1981, Behavioral and neural biology,
M L Smith, and E C Simmel
August 2010, Journal of comparative psychology (Washington, D.C. : 1983),
Copied contents to your clipboard!