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Mice belonging to a number of inbred strains were immunized intradermally with Cl. oedematiens alpha-toxoid. The immunization was repeated 30 days later. On the 20th and the 30th days after the first injection and on the 10th day after the second one the antibody level against the toxoid was determined in the blood of mice by the passive hemagglutination test. The maximum response to the primary immunization was observed in the mice of the C3H strain, and the minimum one--in mice of the DBA/2 strain; the difference was more than 30-fold. The rest of the strains used in the test (A,CBA, BALB/c, AKR, CC57BR) displayed an intermediate level of the immune response. The differences reduced after the repeated immunization. The immune response to this antigen in mice is supposed to be genetically controlled.
R V Petrov, and
E I Panteleev, and
I Ia Moshiashvili, and
G F Shemanova, and
E V Vlasova
January 1959,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
R V Petrov, and
E I Panteleev, and
I Ia Moshiashvili, and
G F Shemanova, and
E V Vlasova
October 1972,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
R V Petrov, and
E I Panteleev, and
I Ia Moshiashvili, and
G F Shemanova, and
E V Vlasova
October 1956,
Annales de l'Institut Pasteur,
R V Petrov, and
E I Panteleev, and
I Ia Moshiashvili, and
G F Shemanova, and
E V Vlasova
January 1974,
Folia biologica,
R V Petrov, and
E I Panteleev, and
I Ia Moshiashvili, and
G F Shemanova, and
E V Vlasova
January 1956,
Biokhimiia (Moscow, Russia),
R V Petrov, and
E I Panteleev, and
I Ia Moshiashvili, and
G F Shemanova, and
E V Vlasova
January 1958,
Biokhimiia (Moscow, Russia),
R V Petrov, and
E I Panteleev, and
I Ia Moshiashvili, and
G F Shemanova, and
E V Vlasova
January 1970,
Journal of comparative pathology,
R V Petrov, and
E I Panteleev, and
I Ia Moshiashvili, and
G F Shemanova, and
E V Vlasova
January 1974,
Folia biologica,
R V Petrov, and
E I Panteleev, and
I Ia Moshiashvili, and
G F Shemanova, and
E V Vlasova
September 1952,
Endocrinology,
R V Petrov, and
E I Panteleev, and
I Ia Moshiashvili, and
G F Shemanova, and
E V Vlasova
July 1977,
European journal of immunology,
