Biomaterial Database

[Kinetics of fibroblast spreading]. 1977

Zh L Bliokh, and V V Smolianinov

For normal mouse fibroblasts four stages of their spreading in vitro are distinguished: the spherical cell stage; the stage of early appearance of processes, Lamellae formation; the stage of maximal cell spreading. Measurements of the duration of every stage were performed by means of time-lapse microcinematography under phase-contrast microscope. It is proved that the first and second stages are elementary ones of Puasson's kinetics and the following ones are complex stages of the same kinetic model. The mean time at these stages is respectively: 25+/-3.2, 12.5+/-1.5; 123+/-8; 162+/-25 minutes.

UI	MeSH Term	Description	Entries
D007700	Kinetics	The rate dynamics in chemical or physical systems.
D002478	Cells, Cultured	Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.	Cultured Cells,Cell, Cultured,Cultured Cell
D005347	Fibroblasts	Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.	Fibroblast
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D051379	Mice	The common name for the genus Mus.	Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus