-transparent.png){kind=logo}
The renal excretion of uric acid was examined during acute i.v. urate (Ua) loading on unilaterally splanchnicotomized ("renal denervation") anaesthetized mongrel dogs. Glomerular filtration rate (GFR) in general was not different in innervated and denervated kidneys, whereas urine flow (V) and urinary excretion of sodium (UNaV) on the splanchnicotomized side were significantly increased at any plasma concentration of Ua. The excretion (UUaV) and tubular transport (TUa) of urate calculated for unit GFR were considerably increased and depressed, respectively, at normal plasma Ua level and during minor urate loading (plasma concentration up to 4.7 mg%). Above this plasma level, i.e. up to 24.6 mg%, no difference in net urate reabsorption between intact and sympathectomized organs was found. It is suggested that both reabsorption and secretion of Ua in denervated kidneys are diminished.
L Szalay, and
E Láng, and
P Bencsáth, and
L Mohai, and
A Fischer, and
L Takács
January 1977,
Pflugers Archiv : European journal of physiology,
L Szalay, and
E Láng, and
P Bencsáth, and
L Mohai, and
A Fischer, and
L Takács
May 1977,
Pflugers Archiv : European journal of physiology,
L Szalay, and
E Láng, and
P Bencsáth, and
L Mohai, and
A Fischer, and
L Takács
January 1976,
Physiologia Bohemoslovaca,
L Szalay, and
E Láng, and
P Bencsáth, and
L Mohai, and
A Fischer, and
L Takács
December 1962,
The American journal of medicine,
L Szalay, and
E Láng, and
P Bencsáth, and
L Mohai, and
A Fischer, and
L Takács
April 1967,
Revue francaise d'etudes cliniques et biologiques,
L Szalay, and
E Láng, and
P Bencsáth, and
L Mohai, and
A Fischer, and
L Takács
November 1987,
Japanese journal of pharmacology,
L Szalay, and
E Láng, and
P Bencsáth, and
L Mohai, and
A Fischer, and
L Takács
December 1963,
Kiserletes orvostudomany,
L Szalay, and
E Láng, and
P Bencsáth, and
L Mohai, and
A Fischer, and
L Takács
June 1974,
Polski tygodnik lekarski (Warsaw, Poland : 1960),
L Szalay, and
E Láng, and
P Bencsáth, and
L Mohai, and
A Fischer, and
L Takács
April 1970,
Klinische Wochenschrift,
L Szalay, and
E Láng, and
P Bencsáth, and
L Mohai, and
A Fischer, and
L Takács
January 1963,
Acta medica Polona,
