-transparent.png){kind=logo}
Acute toxicity of oxibendazole was assessed with single oral doses given to mice (4 to 32 g/kg of body weight), sheep (230 to 600 mg/kg), and cattle (600 mg/kg); there were no ill effects. Subacute toxicity did not occur with multiple doses given 5 days to cattle (30 to 75 mg/kg/day) and to sheep (10 to 50 mg/kg/day). Chronic effects did not occur with daily doses of 3 to 30 mg/kg given 98 days to rats and dogs. Teratogenicity of the compound was studied in mice, rats, and sheep medicated at a dose level of 30 mg of oxibendazole/kg and in cattle given 75 mg/kg on selected dates during pregnancy. Microscopically, rodent fetuses seemed normal, and on gross physical examination, lambs and calves were free of malformations and ossification variations.
V J Theodorides, and
C J DiCuollo, and
T Nawalinski, and
C R Miller, and
J R Murphy, and
J F Freeman, and
J C Killeen, and
W R Rapp
July 1969,
Toxicology and applied pharmacology,
V J Theodorides, and
C J DiCuollo, and
T Nawalinski, and
C R Miller, and
J R Murphy, and
J F Freeman, and
J C Killeen, and
W R Rapp
May 1978,
The Journal of infectious diseases,
V J Theodorides, and
C J DiCuollo, and
T Nawalinski, and
C R Miller, and
J R Murphy, and
J F Freeman, and
J C Killeen, and
W R Rapp
May 1979,
Annals of the New York Academy of Sciences,
V J Theodorides, and
C J DiCuollo, and
T Nawalinski, and
C R Miller, and
J R Murphy, and
J F Freeman, and
J C Killeen, and
W R Rapp
January 1968,
Therapie,
V J Theodorides, and
C J DiCuollo, and
T Nawalinski, and
C R Miller, and
J R Murphy, and
J F Freeman, and
J C Killeen, and
W R Rapp
April 1974,
Toxicology and applied pharmacology,
V J Theodorides, and
C J DiCuollo, and
T Nawalinski, and
C R Miller, and
J R Murphy, and
J F Freeman, and
J C Killeen, and
W R Rapp
August 1966,
Arzneimittel-Forschung,
V J Theodorides, and
C J DiCuollo, and
T Nawalinski, and
C R Miller, and
J R Murphy, and
J F Freeman, and
J C Killeen, and
W R Rapp
August 1991,
Journal of ethnopharmacology,
V J Theodorides, and
C J DiCuollo, and
T Nawalinski, and
C R Miller, and
J R Murphy, and
J F Freeman, and
J C Killeen, and
W R Rapp
August 1995,
Casopis lekaru ceskych,
V J Theodorides, and
C J DiCuollo, and
T Nawalinski, and
C R Miller, and
J R Murphy, and
J F Freeman, and
J C Killeen, and
W R Rapp
June 1973,
Arzneimittel-Forschung,
V J Theodorides, and
C J DiCuollo, and
T Nawalinski, and
C R Miller, and
J R Murphy, and
J F Freeman, and
J C Killeen, and
W R Rapp
January 1992,
Gigiena i sanitariia,
