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We have used computerized tomography (CT) to look for evidence of cerebral demyelination in children with progressive neurologic disorders. Fourteen patients with a clinical diagnosis of a demyelinating disorder were examined by CT, and five had CT findings suggesting cerebral demyelination. In two patients with a so-called myelinoclastic demyelinating disease, CT showed asymmetric, circumscribed areas of diminished radiodensity, and in three patients with a leukodystrophy, scans showed diffuse symmetric areas of low density in the centrum ovale. Autopsy examination in one patient confirmed the diagnosis of sudanophilic leukodystrophy and substantiated the abnormalities suspected from CT.
W C Robertson, and
M R Gomez, and
D F Reese, and
H Okazaki
August 1980,
Archives of neurology,
W C Robertson, and
M R Gomez, and
D F Reese, and
H Okazaki
April 1982,
The American journal of psychiatry,
W C Robertson, and
M R Gomez, and
D F Reese, and
H Okazaki
September 1983,
Heart & lung : the journal of critical care,
W C Robertson, and
M R Gomez, and
D F Reese, and
H Okazaki
January 1987,
Acta gastro-enterologica Belgica,
W C Robertson, and
M R Gomez, and
D F Reese, and
H Okazaki
January 1994,
La Radiologia medica,
W C Robertson, and
M R Gomez, and
D F Reese, and
H Okazaki
January 1982,
The Mount Sinai journal of medicine, New York,
W C Robertson, and
M R Gomez, and
D F Reese, and
H Okazaki
June 1979,
Neurology,
W C Robertson, and
M R Gomez, and
D F Reese, and
H Okazaki
July 1977,
Surgical neurology,
W C Robertson, and
M R Gomez, and
D F Reese, and
H Okazaki
March 1982,
Archives of neurology,
W C Robertson, and
M R Gomez, and
D F Reese, and
H Okazaki
January 2009,
Vestnik Rossiiskoi akademii meditsinskikh nauk,
