Water and sodium absorption in the human intestine. 1968

A H Love, and T G Mitchell, and R A Phillips

1. Studies are reported of total intestinal perfusion in man in which data relating to the absorptive capacity for water and sodium, flow rate transit time and intestinal volume have been obtained.2. A 'bolus' of radiosodium added to the steady-state perfusion has allowed measurement of bidirectional fluxes of sodium ion across the mucosa to be determined.3. The values obtained agree closely with those that can be predicted from small segmental studies reported in the literature.4. Increasing absorption capacity with increasing flow rate does not seem to reflect a true increase in absorption per unit of intestine but rather a progression to more nearly continuous flow conditions.

UI MeSH Term Description Entries
D007408 Intestinal Absorption Uptake of substances through the lining of the INTESTINES. Absorption, Intestinal
D007700 Kinetics The rate dynamics in chemical or physical systems.
D010477 Perfusion Treatment process involving the injection of fluid into an organ or tissue. Perfusions
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012964 Sodium A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23. Sodium Ion Level,Sodium-23,Ion Level, Sodium,Level, Sodium Ion,Sodium 23
D012975 Sodium Isotopes Stable sodium atoms that have the same atomic number as the element sodium, but differ in atomic weight. Na-23 is a stable sodium isotope. Isotopes, Sodium
D014867 Water A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Hydrogen Oxide

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