BIOMAT Database Logo BIOMAT Database Logo

Failure of probenecid to inhibit the rate of metabolism of tolbutamide in man. 1968

R Brook, and J J Schrogie, and H M Solomon

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011339 Probenecid The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy. Benecid,Benemid,Benuryl,Pro-Cid,Probecid,Probenecid Weimer
D003864 Depression, Chemical The decrease in a measurable parameter of a PHYSIOLOGICAL PROCESS, including cellular, microbial, and plant; immunological, cardiovascular, respiratory, reproductive, urinary, digestive, neural, musculoskeletal, ocular, and skin physiological processes; or METABOLIC PROCESS, including enzymatic and other pharmacological processes, by a drug or other chemical. Chemical Depression,Chemical Depressions,Depressions, Chemical
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor
D014044 Tolbutamide A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290) Apo-Tolbutamide,Artosin,Diabetol,Diaval,Dolipol,Orabet,Orinase,Rastinon,Tolbutamid R.A.N.

Related Publications

R Brook, and J J Schrogie, and H M Solomon
The metabolism of probenecid in man.
July 1971, Annals of the New York Academy of Sciences,
R Brook, and J J Schrogie, and H M Solomon
[Tolbutamide metabolism in kidney failure].
December 1968, Die Medizinische Welt,
R Brook, and J J Schrogie, and H M Solomon
Increased rate of tolbutamide metabolism in alcoholic patients.
January 1969, JAMA,
R Brook, and J J Schrogie, and H M Solomon
Unaltered metabolism of antipyrine and tolbutamide in fasting man.
June 1975, Clinical pharmacology and therapeutics,
R Brook, and J J Schrogie, and H M Solomon
Failure of exogenous insulin to inhibit insulin secretion in man.
November 1977, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
R Brook, and J J Schrogie, and H M Solomon
The metabolism of (ureyl-14C)tolbutamide in vitro and in vivo in man.
July 1973, Life sciences,
R Brook, and J J Schrogie, and H M Solomon
Aspirin and probenecid inhibit organic anion transporter 3-mediated renal uptake of cilostazol and probenecid induces metabolism of cilostazol in the rat.
June 2014, Drug metabolism and disposition: the biological fate of chemicals,
R Brook, and J J Schrogie, and H M Solomon
The influence of probenecid on the metabolism of serotonin, dopamine and their precursors in man.
January 1973, Psychopharmacologia,
R Brook, and J J Schrogie, and H M Solomon
Rate of papaverine metabolism in man.
September 1953, Journal of applied physiology,
R Brook, and J J Schrogie, and H M Solomon
Effect of probenecid on response to bumetanide in man.
July 1981, Journal of clinical pharmacology,
Copied contents to your clipboard!