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One-hundred and eight-five pairs of gas samples were collected from inspired gas (10 cm behind the head at nose level) and end-tidal gas of persons administering anesthesia in 3 operating rooms during daily routine anesthesia. Mean operating-room N2O concentrations from 22 to 144 ppm (volume/volume [V/V]) were measured by gas chromatography, and large moment-to-moment variations (temporal gradients) were seen in individual operating rooms. Mean end-tidal N2O concentrations from 51 to 114 ppm (V/V) were observed. There were low correlations between inspired and end-tidal N2O concentrations (r values as low as r = 0.35). This poor relationship is presumably due to spatial and temporal gradients of N2O in the operating rooms. We conclude that the temporal and spatial gradients in N2O concentrations within active operating rooms are sufficiently large to invalidate estimation of exposure of anesthetic personnel to N2O from "spot" or "grab" samples collected in the breathing area.
F M Beynen, and
T J Knopp, and
K Rehder
February 1995,
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F M Beynen, and
T J Knopp, and
K Rehder
January 1997,
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F M Beynen, and
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K Rehder
January 1978,
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F M Beynen, and
T J Knopp, and
K Rehder
September 1992,
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F M Beynen, and
T J Knopp, and
K Rehder
August 1977,
Canadian Medical Association journal,
F M Beynen, and
T J Knopp, and
K Rehder
August 1977,
Canadian Medical Association journal,
F M Beynen, and
T J Knopp, and
K Rehder
January 2016,
Current emergency and hospital medicine reports,
F M Beynen, and
T J Knopp, and
K Rehder
January 1980,
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F M Beynen, and
T J Knopp, and
K Rehder
February 1985,
Anesthesiology,
F M Beynen, and
T J Knopp, and
K Rehder
January 1978,
Acta anaesthesiologica Scandinavica,
