-transparent.png){kind=logo}
1. Leukemic Swiss mice of ICR/Ha strain which had been injected at birth with a lymphoid-leukemia-inducing virus preparation yielded sera which produced elevations of serum colony-stimulating activity within 16 hr and significant plasma-LDH-enzyme elevation at 4 days when injected intraperitoneally into normal ICR/Ha Swiss mice. Colony-stimulating activity was assayed in vitro by the stimulation of hemopoietic colony formation by DBA/1 bone marrow cells. 2. The inducing agent in leukemic serum was passageable, filterable, sedimentable, and heat-, ether-, and UV-labile. 3. A similar agent was recovered from normal Swiss serum after blind serial passages through normal mice. 4. LDH elevating virus induced a similar elevation of serum colony-stimulating activity when injected at high titers, and cross-resistance was demonstrated between LDH virus and the passaged leukemic serum agent.
R Foster, and
D Metcalf, and
R Kirchmyer
November 1980,
Experimental hematology,
R Foster, and
D Metcalf, and
R Kirchmyer
January 1978,
Acta haematologica Polonica,
R Foster, and
D Metcalf, and
R Kirchmyer
February 1983,
Experimental hematology,
R Foster, and
D Metcalf, and
R Kirchmyer
November 1978,
The Journal of laboratory and clinical medicine,
R Foster, and
D Metcalf, and
R Kirchmyer
June 1978,
Proceedings of the National Academy of Sciences of the United States of America,
R Foster, and
D Metcalf, and
R Kirchmyer
September 1980,
British journal of haematology,
R Foster, and
D Metcalf, and
R Kirchmyer
January 1980,
Nouvelle revue francaise d'hematologie,
R Foster, and
D Metcalf, and
R Kirchmyer
June 1975,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
R Foster, and
D Metcalf, and
R Kirchmyer
January 1986,
Progress in clinical and biological research,
R Foster, and
D Metcalf, and
R Kirchmyer
July 1968,
British medical journal,
