-transparent.png){kind=logo}
Purified human IgG from both serum and the culture of human splenic cells was radiolabeled with 125I. Incubation of radiolabeled IgG from patients with idiopathic thrombocytopenic purpura (ITP) with normal homologous platelets or bone marrow cells resulted in significant (P less than .001) binding when compared with control IgG. Radioautographs showed that the radioactivity was associated with the platelets or megakaryocytes. The antiplatelet antibody in ITP has specificity for antigens associated with both platelets and megakaryocytes and suggests that thrombopolesis may also be affected in this disease.
Related Publications
R McMillan, and
G A Luiken, and
R Levy, and
R Yelenosky, and
R L Longmire
January 1984,
Folia haematologica (Leipzig, Germany : 1928),
R McMillan, and
G A Luiken, and
R Levy, and
R Yelenosky, and
R L Longmire
January 1989,
Folia haematologica (Leipzig, Germany : 1928),
R McMillan, and
G A Luiken, and
R Levy, and
R Yelenosky, and
R L Longmire
January 1983,
Haematologica,
R McMillan, and
G A Luiken, and
R Levy, and
R Yelenosky, and
R L Longmire
January 1946,
Blood,
R McMillan, and
G A Luiken, and
R Levy, and
R Yelenosky, and
R L Longmire
May 1978,
Nihon rinsho. Japanese journal of clinical medicine,
R McMillan, and
G A Luiken, and
R Levy, and
R Yelenosky, and
R L Longmire
January 2009,
Indian journal of pathology & microbiology,
R McMillan, and
G A Luiken, and
R Levy, and
R Yelenosky, and
R L Longmire
October 2006,
Indian journal of pathology & microbiology,
R McMillan, and
G A Luiken, and
R Levy, and
R Yelenosky, and
R L Longmire
February 1997,
Blood,
R McMillan, and
G A Luiken, and
R Levy, and
R Yelenosky, and
R L Longmire
February 1977,
Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society,
R McMillan, and
G A Luiken, and
R Levy, and
R Yelenosky, and
R L Longmire
January 1967,
Annales medicinae internae Fenniae,
