[Alkaptonuria, ochronosis and degenerative disorders of the spinal column and joints].
1968
J J Festen, and
J G Bouman, and
R L Nienhuis
UI
MeSH Term
Description
Entries
D008159
Lumbar Vertebrae
VERTEBRAE in the region of the lower BACK below the THORACIC VERTEBRAE and above the SACRAL VERTEBRAE.
Vertebrae, Lumbar
D008297
Male
Males
D008875
Middle Aged
An adult aged 45 - 64 years.
Middle Age
D009794
Ochronosis
The yellowish discoloration of connective tissue due to deposition of HOMOGENTISIC ACID (a brown-black pigment). This is due to defects in the metabolism of PHENYLALANINE and TYROSINE. Ochronosis occurs in ALKAPTONURIA, but has also been associated with exposure to certain chemicals (e.g., PHENOL, trinitrophenol, BENZENE DERIVATIVES).
Ochronoses
D002845
Chromatography
Techniques used to separate mixtures of substances based on differences in the relative affinities of the substances for mobile and stationary phases. A mobile phase (fluid or gas) passes through a column containing a stationary phase of porous solid or liquid coated on a solid support. Usage is both analytical for small amounts and preparative for bulk amounts.
Chromatographies
D005260
Female
Females
D006615
Hip
The projecting part on each side of the body, formed by the side of the pelvis and the top portion of the femur.
Coxa,Coxas,Hips
D006801
Humans
Members of the species Homo sapiens.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328
Adult
A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.
Adults
D000474
Alkaptonuria
An inborn error of amino acid metabolism resulting from a defect in the enzyme HOMOGENTISATE 1,2-DIOXYGENASE, an enzyme involved in the breakdown of PHENYLALANINE and TYROSINE. It is characterized by accumulation of HOMOGENTISIC ACID in the urine, OCHRONOSIS in various tissues, and ARTHRITIS.