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Obviously there is need for a reliable means of automating complement-fixation tests. This paper offers an account of experience with an AutoAnalyzer adapted for this purpose. Results of syphilis screening tests done by the AutoAnalyzer compared with those of tests performed manually showed satisfactory agreement, the automated method being slightly less specific in our hands. There were no false negative results with the AutoAnalyzer if both Maltaner and Reiter protein antigens were used. The current design of the AutoAnalyzer contains three major shortcomings if it is to be used for large numbers of complement-fixation tests. First and foremost is the relatively slow sampling rate compatible with adequate sample discrimination. Second is the necessity for frequently replenishing the machine with samples. Third is the need for adjusting or cleaning the flow-cell during use.
C E Taylor, and
J W Kershaw, and
G V Heimer
February 1970,
Journal of clinical pathology,
C E Taylor, and
J W Kershaw, and
G V Heimer
November 1971,
Nordisk medicin,
C E Taylor, and
J W Kershaw, and
G V Heimer
June 1967,
Analytical biochemistry,
C E Taylor, and
J W Kershaw, and
G V Heimer
May 1970,
The Proceedings of the Nutrition Society,
C E Taylor, and
J W Kershaw, and
G V Heimer
July 1966,
Journal of clinical pathology,
C E Taylor, and
J W Kershaw, and
G V Heimer
January 1969,
Annales de biologie clinique,
C E Taylor, and
J W Kershaw, and
G V Heimer
February 1975,
Hippokrates,
C E Taylor, and
J W Kershaw, and
G V Heimer
November 1982,
Journal of pharmacological methods,
C E Taylor, and
J W Kershaw, and
G V Heimer
April 1971,
The Journal of the Royal College of General Practitioners,
C E Taylor, and
J W Kershaw, and
G V Heimer
April 1967,
Environmental science & technology,
