Biomaterial Database

Determination of vitamin B 12 absorption by a simple whole body counter. 1968

N D Finlayson, and D J Shearman, and J D Simpson, and R H Girdwood

This paper reports the results of estimating vitamin B(12) absorption by whole body counting in patients without known gastrointestinal disorder, and in patients with pernicious anaemia, idiopathic achlorhydria, achlorhydria following gastric operations, and various forms of small intestinal disease. Patients with pernicious anaemia absorbed less than 30% of the test dose; they could be distinguished from patients without gastrointestinal abnormality and from most achlorhydric patients who secreted more than 300 mg units of intrinsic factor in the post-histamine hour. Nevertheless, the wide range of normal absorption and the variable absorption from the normal gastrointestinal tract is emphasized and discussed. There is no relation between histamine-stimulated intrinsic factor production and vitamin B(12) absorption in patients with small intestinal disease.

UI	MeSH Term	Description	Entries
D007408	Intestinal Absorption	Uptake of substances through the lining of the INTESTINES.	Absorption, Intestinal
D007410	Intestinal Diseases	Pathological processes in any segment of the INTESTINE from DUODENUM to RECTUM.	Disease, Intestinal,Diseases, Intestinal,Intestinal Disease
D008286	Malabsorption Syndromes	General term for a group of MALNUTRITION syndromes caused by failure of normal INTESTINAL ABSORPTION of nutrients.	Malabsorption Syndrome,Syndrome, Malabsorption,Syndromes, Malabsorption
D008722	Methods	A series of steps taken in order to conduct research.	Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D011178	Postgastrectomy Syndromes	Sequelae of gastrectomy from the second week after operation on. Include recurrent or anastomotic ulcer, postprandial syndromes (DUMPING SYNDROME and late postprandial hypoglycemia), disordered bowel action, and nutritional deficiencies.	Postgastrectomy Syndrome,Syndrome, Postgastrectomy,Syndromes, Postgastrectomy
D011874	Radiometry	The measurement of radiation by photography, as in x-ray film and film badge, by Geiger-Mueller tube, and by SCINTILLATION COUNTING.	Geiger-Mueller Counters,Nuclear Track Detection,Radiation Dosimetry,Dosimetry, Radiation,Geiger Counter,Geiger-Mueller Counter Tube,Geiger-Mueller Probe,Geiger-Mueller Tube,Radiation Counter,Counter Tube, Geiger-Mueller,Counter Tubes, Geiger-Mueller,Counter, Geiger,Counter, Radiation,Counters, Geiger,Counters, Geiger-Mueller,Counters, Radiation,Detection, Nuclear Track,Dosimetries, Radiation,Geiger Counters,Geiger Mueller Counter Tube,Geiger Mueller Counters,Geiger Mueller Probe,Geiger Mueller Tube,Geiger-Mueller Counter Tubes,Geiger-Mueller Probes,Geiger-Mueller Tubes,Probe, Geiger-Mueller,Probes, Geiger-Mueller,Radiation Counters,Radiation Dosimetries,Tube, Geiger-Mueller,Tube, Geiger-Mueller Counter,Tubes, Geiger-Mueller,Tubes, Geiger-Mueller Counter
D003036	Cobalt Isotopes	Stable cobalt atoms that have the same atomic number as the element cobalt, but differ in atomic weight. Co-59 is a stable cobalt isotope.	Isotopes, Cobalt
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000126	Achlorhydria	A lack of HYDROCHLORIC ACID in GASTRIC JUICE despite stimulation of gastric secretion.	Achylia Gastrica,Hypochlorhydria
D000752	Anemia, Pernicious	A megaloblastic anemia occurring in children but more commonly in later life, characterized by histamine-fast achlorhydria, in which the laboratory and clinical manifestations are based on malabsorption of vitamin B 12 due to a failure of the gastric mucosa to secrete adequate and potent intrinsic factor. (Dorland, 27th ed)	Addison's Anemia,Anemia, Addison's,Pernicious Anemia,Addison Anemia,Addisons Anemia,Anemia, Addison,Anemia, Addisons

Related Publications

N D Finlayson, and D J Shearman, and J D Simpson, and R H Girdwood

Studies on iron and vitamin B 12 absorption in patients with chronic enteropathies using whole body counter.

January 1972, Revue roumaine de medecine interne (1964),

N D Finlayson, and D J Shearman, and J D Simpson, and R H Girdwood

[Studies of vitamin B 12 absorption by a whole-body counter. (2). Clinical application with special reference to the effect of pancreatic enzymes on vitamin B 12 absorption in patients after total pancreatectomy].

December 1975, Kaku igaku. The Japanese journal of nuclear medicine,

N D Finlayson, and D J Shearman, and J D Simpson, and R H Girdwood

[Vitamin B12 absorption test by a whole body counter (plastic scintillator). (1) Experimental study].

August 1975, Kaku igaku. The Japanese journal of nuclear medicine,

N D Finlayson, and D J Shearman, and J D Simpson, and R H Girdwood

A fast method of measuring vitamin B12 absorption using a whole-body counter.

February 1983, Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics,

N D Finlayson, and D J Shearman, and J D Simpson, and R H Girdwood

Assessment of vitamin B12 absorption in tropical sprue utilizing a whole body counter.

February 1976, Boletin de la Asociacion Medica de Puerto Rico,

N D Finlayson, and D J Shearman, and J D Simpson, and R H Girdwood

The study of 57-Co-vitamin B12-absorption using a whole-body counter.

July 1969, Physics in medicine and biology,

N D Finlayson, and D J Shearman, and J D Simpson, and R H Girdwood

Vitamin B-12 absorption by inhalation.

January 1967, British journal of haematology,

N D Finlayson, and D J Shearman, and J D Simpson, and R H Girdwood

[Simultaneous measurement of vitamin B 12 and iron absorption in a whole-body counter after total gastrectomy, gastric resection, and in cases of atrophic gastritis].

January 1970, Deutsche medizinische Wochenschrift (1946),