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6 patients with radiolucent cholelithiasis underwent randomized successive 3-week trials on each of the following medications: beta-glycerophosphate, linoleic acid, or purified soybean lecithin. Bile-rich duodenal fluid was obtained prior to the study and following each treatment period. Soybean lecithin feeding effected a qualitative change in biliary lecithin with increased fatty acid unsaturation, but no significant improvement in biliary cholesterol saturation or lipid composition changes including a proportionate increase in biliary phospholipids resulted from any treatment program. A 6-month therapeutic trial with soybean lecithin plus cholic acid failed to show a therapeutic response indicative of gallstone dissolution in the 6 patients.
K R Holan, and
R T Holzbach, and
J Y Hsieh, and
D K Welch, and
J G Turcotte
January 1983,
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition,
K R Holan, and
R T Holzbach, and
J Y Hsieh, and
D K Welch, and
J G Turcotte
November 1973,
The Journal of clinical investigation,
K R Holan, and
R T Holzbach, and
J Y Hsieh, and
D K Welch, and
J G Turcotte
July 1938,
The Biochemical journal,
K R Holan, and
R T Holzbach, and
J Y Hsieh, and
D K Welch, and
J G Turcotte
July 1973,
Polski tygodnik lekarski (Warsaw, Poland : 1960),
K R Holan, and
R T Holzbach, and
J Y Hsieh, and
D K Welch, and
J G Turcotte
April 1978,
Clinical science and molecular medicine,
K R Holan, and
R T Holzbach, and
J Y Hsieh, and
D K Welch, and
J G Turcotte
September 1978,
The Journal of the Association of Physicians of India,
K R Holan, and
R T Holzbach, and
J Y Hsieh, and
D K Welch, and
J G Turcotte
October 1994,
Mayo Clinic proceedings,
K R Holan, and
R T Holzbach, and
J Y Hsieh, and
D K Welch, and
J G Turcotte
October 1985,
The Journal of nutrition,
K R Holan, and
R T Holzbach, and
J Y Hsieh, and
D K Welch, and
J G Turcotte
February 1982,
Revista espanola de las enfermedades del aparato digestivo,
K R Holan, and
R T Holzbach, and
J Y Hsieh, and
D K Welch, and
J G Turcotte
September 1973,
British medical journal,
