BIOMAT Database Logo BIOMAT Database Logo

Familial transmission of a translocation Y/14. 1979

C H Buys, and G J Anders, and J M Borkent-Ypma, and J A Blenkers-Platter, and A Y van der Hoek-van der Veen

A translocation of heterochromatic material, brightly fluorescent after actinomycin D-DAPI staining, to the short arm of chromosome 14 was prenatally detected during cytogenetic examination of cells obtained by amniocentesis on the indication of advanced maternal age. Besides this abnormal chromosome, 43 autosomes and two X chromosomes were present. Silver staining made clear that an active nucleolus-organizing region was included in the translocation product. Both the intense fluorescence and the size of the translocated extra heterochromatic block were indicative of a Yq origin. Upon cytogenetic investigation of the parents, the mother appeared to carry the same t(Y;14) chromosome. Therefore, we expected a normal girl to be born. This was confirmed after birth.

UI MeSH Term Description Entries
D008297 Male Males
D008423 Maternal Age The age of the mother in PREGNANCY. Age, Maternal,Ages, Maternal,Maternal Ages
D009697 Nucleolus Organizer Region The chromosome region which is active in nucleolus formation and which functions in the synthesis of ribosomal RNA. Nucleolar Organizer,Nucleolar Organizers,Nucleolus Organizer Regions,Organizer Region, Nucleolus,Organizer Regions, Nucleolus,Organizer, Nucleolar,Organizers, Nucleolar,Region, Nucleolus Organizer,Regions, Nucleolus Organizer
D010641 Phenotype The outward appearance of the individual. It is the product of interactions between genes, and between the GENOTYPE and the environment. Phenotypes
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D011296 Prenatal Diagnosis Determination of the nature of a pathological condition or disease in the postimplantation EMBRYO; FETUS; or pregnant female before birth. Diagnosis, Prenatal,Fetal Diagnosis,Fetal Imaging,Fetal Screening,Intrauterine Diagnosis,Antenatal Diagnosis,Antenatal Screening,Diagnosis, Antenatal,Diagnosis, Intrauterine,Prenatal Screening,Antenatal Diagnoses,Antenatal Screenings,Diagnosis, Fetal,Fetal Diagnoses,Fetal Imagings,Fetal Screenings,Imaging, Fetal,Intrauterine Diagnoses,Prenatal Diagnoses,Prenatal Screenings,Screening, Antenatal,Screening, Fetal,Screening, Prenatal
D002901 Chromosomes, Human, 13-15 The medium-sized, acrocentric human chromosomes, called group D in the human chromosome classification. This group consists of chromosome pairs 13, 14, and 15. Chromosomes D,Group D Chromosomes,Chromosome, Group D,Chromosomes, Group D,Group D Chromosome
D005260 Female Females
D006570 Heterochromatin The portion of chromosome material that remains condensed and is transcriptionally inactive during INTERPHASE. Heterochromatins
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

C H Buys, and G J Anders, and J M Borkent-Ypma, and J A Blenkers-Platter, and A Y van der Hoek-van der Veen
A novel Y/13 familial translocation.
October 1987, American journal of obstetrics and gynecology,
C H Buys, and G J Anders, and J M Borkent-Ypma, and J A Blenkers-Platter, and A Y van der Hoek-van der Veen
Familial transmission of a (21q22q) translocation.
January 1975, Cytogenetics and cell genetics,
C H Buys, and G J Anders, and J M Borkent-Ypma, and J A Blenkers-Platter, and A Y van der Hoek-van der Veen
A familial Y-autosome translocation in man.
January 1971, Clinical genetics,
C H Buys, and G J Anders, and J M Borkent-Ypma, and J A Blenkers-Platter, and A Y van der Hoek-van der Veen
Familial Y/22 translocation in a woman.
December 1978, Journal de genetique humaine,
C H Buys, and G J Anders, and J M Borkent-Ypma, and J A Blenkers-Platter, and A Y van der Hoek-van der Veen
A familial Y-22 translocation in man.
January 1973, Hereditas,
C H Buys, and G J Anders, and J M Borkent-Ypma, and J A Blenkers-Platter, and A Y van der Hoek-van der Veen
Case of (Y;1) familial translocation.
May 1993, American journal of medical genetics,
C H Buys, and G J Anders, and J M Borkent-Ypma, and J A Blenkers-Platter, and A Y van der Hoek-van der Veen
[Prenatal diagnosis of a familial Y/15 translocation].
February 1988, Rinsho byori. The Japanese journal of clinical pathology,
C H Buys, and G J Anders, and J M Borkent-Ypma, and J A Blenkers-Platter, and A Y van der Hoek-van der Veen
Follow-up investigation of a familial translocation 14/18.
January 1977, Acta geneticae medicae et gemellologiae,
C H Buys, and G J Anders, and J M Borkent-Ypma, and J A Blenkers-Platter, and A Y van der Hoek-van der Veen
Familial transmission of a non-Robertsonian translocation dicentric.
March 1986, Clinical genetics,
C H Buys, and G J Anders, and J M Borkent-Ypma, and J A Blenkers-Platter, and A Y van der Hoek-van der Veen
Down syndrome associated with a familial 14/21 translocation.
January 1981, The Ulster medical journal,
Copied contents to your clipboard!