[Studies in man on acquired immunologic tolerance].
1968
M Soledad Córdova, and
B Pirofsky, and
A Aguayo, and
L M Sentíes
UI
MeSH Term
Description
Entries
D007108
Immune Tolerance
The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.
Exchange of substances between the maternal blood and the fetal blood at the PLACENTA via PLACENTAL CIRCULATION. The placental barrier excludes microbial or viral transmission.