Radiographical examinations of the rat with adjuvant disease reveal characteristic changes in the joints and soft tissues which are useful for the evaluation of this experimental arthritis model. Sequential radiographical analysis with estimation of radiological joint score allows a close follow-up of the disease, which parallels some clinical parameters. Being objective and easy to be documented this method shows several advantages over the conventional evaluation methods. Furthermore, it enables an insight into the paraarticular and spine involvement, which otherwise remains uncovered. The radiographical evaluations might provide some additional and eventually essential information in the study of some drug effect in this disease. Our data should encourage the use of this method for the evaluation of the adjuvant disease in the rat.