BIOMAT Database Logo BIOMAT Database Logo

Highly selective in vivo ethylation of rat liver nuclear protein by ethionine. 1969

M Friedman, and K H Shull, and E Farber

UI MeSH Term Description Entries
D008099 Liver A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances. Livers
D008297 Male Males
D008715 Methionine A sulfur-containing essential L-amino acid that is important in many body functions. L-Methionine,Liquimeth,Methionine, L-Isomer,Pedameth,L-Isomer Methionine,Methionine, L Isomer
D009698 Nucleoproteins Proteins conjugated with nucleic acids. Nucleoprotein
D002247 Carbon Isotopes Stable carbon atoms that have the same atomic number as the element carbon but differ in atomic weight. C-13 is a stable carbon isotope. Carbon Isotope,Isotope, Carbon,Isotopes, Carbon
D002273 Carcinogens Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included. Carcinogen,Oncogen,Oncogens,Tumor Initiator,Tumor Initiators,Tumor Promoter,Tumor Promoters,Initiator, Tumor,Initiators, Tumor,Promoter, Tumor,Promoters, Tumor
D005001 Ethionine 2-Amino-4-(ethylthio)butyric acid. An antimetabolite and methionine antagonist that interferes with amino acid incorporation into proteins and with cellular ATP utilization. It also produces liver neoplasms.
D005998 Glycine A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter. Aminoacetic Acid,Glycine, Monopotassium Salt,Glycine Carbonate (1:1), Monosodium Salt,Glycine Carbonate (2:1), Monolithium Salt,Glycine Carbonate (2:1), Monopotassium Salt,Glycine Carbonate (2:1), Monosodium Salt,Glycine Hydrochloride,Glycine Hydrochloride (2:1),Glycine Phosphate,Glycine Phosphate (1:1),Glycine Sulfate (3:1),Glycine, Calcium Salt,Glycine, Calcium Salt (2:1),Glycine, Cobalt Salt,Glycine, Copper Salt,Glycine, Monoammonium Salt,Glycine, Monosodium Salt,Glycine, Sodium Hydrogen Carbonate,Acid, Aminoacetic,Calcium Salt Glycine,Cobalt Salt Glycine,Copper Salt Glycine,Hydrochloride, Glycine,Monoammonium Salt Glycine,Monopotassium Salt Glycine,Monosodium Salt Glycine,Phosphate, Glycine,Salt Glycine, Monoammonium,Salt Glycine, Monopotassium,Salt Glycine, Monosodium
D006146 Guanidines A family of iminourea derivatives. The parent compound has been isolated from mushrooms, corn germ, rice hulls, mussels, earthworms, and turnip juice. Derivatives may have antiviral and antifungal properties.
D000478 Alkylation The covalent bonding of an alkyl group to an organic compound. It can occur by a simple addition reaction or by substitution of another functional group. Alkylations

Related Publications

M Friedman, and K H Shull, and E Farber
Ethylation in vivo of purines in rat-liver RNA by L-ethionine.
November 1968, Biochemical and biophysical research communications,
M Friedman, and K H Shull, and E Farber
Chemical carcinogenesis. I. Rat liver tRNA ethylation by ethionine.
June 1984, Bollettino della Societa italiana di biologia sperimentale,
M Friedman, and K H Shull, and E Farber
Incorporation in vivo of methionine and ethionine into and the methylation and ethylation of rat liver nuclear proteins.
October 1968, The Biochemical journal,
M Friedman, and K H Shull, and E Farber
Suppressive effect of copper on ethylation of rat liver DNA with ethionine in vivo.
October 1977, Gan,
M Friedman, and K H Shull, and E Farber
Evidence for ethylation of rat liver deoxyribonucleic acid after administration of ethionine.
June 1971, The Biochemical journal,
M Friedman, and K H Shull, and E Farber
Studies of the ethylation of rat liver transfer ribonucleic acid after administration of L-ethionine.
June 1972, The Biochemical journal,
M Friedman, and K H Shull, and E Farber
Interaction between ethionine and rat liver ribonucleic acid and protein in vivo.
October 1967, Cancer research,
M Friedman, and K H Shull, and E Farber
Suppression of autophagy by ethionine administration in male rat liver in vivo.
May 2000, Toxicology,
M Friedman, and K H Shull, and E Farber
Selective inhibition of rat liver nuclear RNA polymerase II by actinomycin D in vivo.
July 1980, Carcinogenesis,
M Friedman, and K H Shull, and E Farber
1,7-Diethylguanosine formation in tRNA chemical ethylation by ethionine and ethylnitrosourea.
June 1985, Biochimica et biophysica acta,
Copied contents to your clipboard!