[Local therapy of metastatic pleural effusions with zusammenfassung proteolytic enzymes (author's transl)]. 1977

O Kokron

From 1970 to 1976, 268 patients with pleural effusions underwent local therapy with the polyenzyme preparation Wobemugos; 235 patients were evaluable regarding the effectiveness of this therapy. In 115 of the cases, the primary tumour was carcinoma of the bronchus, in 86, carcinoma of the breast, in 9, mesothelioma and carcinoma of the ovary each, and in 16, other malignancies. There was a total remission of pleural effusions in 42% of the cases, a partial one in 41%, and no effect in 17%. In spite of the relatively large number of patients, some difficulties in interpreting the present results still remain and will be discussed in this paper.

UI MeSH Term Description Entries
D009362 Neoplasm Metastasis The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. Metastase,Metastasis,Metastases, Neoplasm,Metastasis, Neoplasm,Neoplasm Metastases,Metastases
D010447 Peptide Hydrolases Hydrolases that specifically cleave the peptide bonds found in PROTEINS and PEPTIDES. Examples of sub-subclasses for this group include EXOPEPTIDASES and ENDOPEPTIDASES. Peptidase,Peptidases,Peptide Hydrolase,Protease,Proteases,Proteinase,Proteinases,Proteolytic Enzyme,Proteolytic Enzymes,Esteroproteases,Enzyme, Proteolytic,Hydrolase, Peptide
D010996 Pleural Effusion Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself. Effusion, Pleural,Effusions, Pleural,Pleural Effusions
D010997 Pleural Neoplasms Neoplasms of the thin serous membrane that envelopes the lungs and lines the thoracic cavity. Pleural neoplasms are exceedingly rare and are usually not diagnosed until they are advanced because in the early stages they produce no symptoms. Neoplasms, Pleural,Neoplasm, Pleural,Pleural Neoplasm
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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