Biomaterial Database

Use of hamsters of potency assay of Eastern and Western equine encephalitis vaccines. 1969

F E Cole, and R W McKinney

An antigen extinction test in hamsters is described. Comparative potency assays with guinea pigs and hamsters showed the latter to be a suitable, advantageous replacement animal in these assays.

UI	MeSH Term	Description	Entries
D004668	Encephalitis Viruses	A collection of single-stranded RNA viruses scattered across the Bunyaviridae, Flaviviridae, and Togaviridae families whose common property is the ability to induce encephalitic conditions in infected hosts.	Encephalitis Virus,Virus, Encephalitis,Viruses, Encephalitis
D004683	Encephalomyelitis, Equine	A group of ALPHAVIRUS INFECTIONS which affect horses and man, transmitted via the bites of mosquitoes. Disorders in this category are endemic to regions of South America and North America. In humans, clinical manifestations vary with the type of infection, and range from a mild influenza-like syndrome to a fulminant encephalitis. (From Joynt, Clinical Neurology, 1996, Ch26, pp8-10)	Encephalitis, Equine,Equine Encephalomyelitis Virus Infections,Equine Encephalitis,Equine Encephalomyelitis Viral Infections,Infections, Equine Encephalomyelitis Virus,Equine Encephalomyelitis
D006168	Guinea Pigs	A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research.	Cavia,Cavia porcellus,Guinea Pig,Pig, Guinea,Pigs, Guinea
D006224	Cricetinae	A subfamily in the family MURIDAE, comprising the hamsters. Four of the more common genera are Cricetus, CRICETULUS; MESOCRICETUS; and PHODOPUS.	Cricetus,Hamsters,Hamster
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D014765	Viral Vaccines	Suspensions of attenuated or killed viruses administered for the prevention or treatment of infectious viral disease.	Viral Vaccine,Vaccine, Viral,Vaccines, Viral