8679 post mortem dissections have been performed in the Institute during the rescent 25 years; 563 of them have been cases of poisoning (=6.5% of totality). They were grouped for the years 1950--1965 and 1966--1975. Suicidal poisoning showed an increasing, poisoning in children a decreasing tendency during the last 25 years. Suicides were mainly performed with hypnotics. Carbon monoxide poisoning dominated in the group of accidental poisoning.