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4,4-dimethyl-5-alpha-cholesta-8,14-dien-3-beta-ol. A new precursor of cholesterol in mammalian tissues. 1969

A Fiecchi, and L Canonica, and A Scala, and F Cattabeni, and E G Paoletti, and R Paoletti

UI MeSH Term Description Entries
D008099 Liver A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances. Livers
D002776 Cholestanes Derivatives of the saturated steroid cholestane with methyl groups at C-18 and C-19 and an iso-octyl side chain at C-17.
D002784 Cholesterol The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils. Epicholesterol
D002845 Chromatography Techniques used to separate mixtures of substances based on differences in the relative affinities of the substances for mobile and stationary phases. A mobile phase (fluid or gas) passes through a column containing a stationary phase of porous solid or liquid coated on a solid support. Usage is both analytical for small amounts and preparative for bulk amounts. Chromatographies
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D013261 Sterols Steroids with a hydroxyl group at C-3 and most of the skeleton of cholestane. Additional carbon atoms may be present in the side chain. (IUPAC Steroid Nomenclature, 1987) Sterol
D014316 Tritium The radioactive isotope of hydrogen also known as hydrogen-3. It contains two NEUTRONS and one PROTON in its nucleus and decays to produce low energy BETA PARTICLES. Hydrogen-3,Hydrogen 3
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus
D066298 In Vitro Techniques Methods to study reactions or processes taking place in an artificial environment outside the living organism. In Vitro Test,In Vitro Testing,In Vitro Tests,In Vitro as Topic,In Vitro,In Vitro Technique,In Vitro Testings,Technique, In Vitro,Techniques, In Vitro,Test, In Vitro,Testing, In Vitro,Testings, In Vitro,Tests, In Vitro,Vitro Testing, In

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A Fiecchi, and L Canonica, and A Scala, and F Cattabeni, and E G Paoletti, and R Paoletti
The role of a cholesta-8,14-dien-3-beta-ol system in cholesterol biosynthesis.
March 1969, The Biochemical journal,
A Fiecchi, and L Canonica, and A Scala, and F Cattabeni, and E G Paoletti, and R Paoletti
Inhibition of enzymatic reduction of delta 14-double bond of 5 alpha-cholesta-8,14-dien-3 beta-ol and 5 alpha-cholesta-7,14-dien-3 beta-ol by AY-9944.
January 1975, Lipids,
A Fiecchi, and L Canonica, and A Scala, and F Cattabeni, and E G Paoletti, and R Paoletti
Studies of the metabolism of 5 -cholesta-8,14-dien-3 -ol and 5 -cholesta-7,14-dien-3 -ol in rat liver homogenate preparations.
November 1971, The Journal of biological chemistry,
A Fiecchi, and L Canonica, and A Scala, and F Cattabeni, and E G Paoletti, and R Paoletti
A novel olefinic rearrangement. The enzymic conversion of cholesta-7,9-dien-3 -ol into cholesta-8,14-dien-3 -ol.
September 1972, The Biochemical journal,
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Studies on the enzymatic conversion of 5 alpha-cholesta-8, 14-dien-3 beta-ol to cholesterol.
December 1970, The Journal of biological chemistry,
A Fiecchi, and L Canonica, and A Scala, and F Cattabeni, and E G Paoletti, and R Paoletti
4,4-Dimethyl-5 alpha-ergosta-8,24(28)-dien-3 beta-ol from the fungus Marasmius oreades.
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Synthesis of 14 beta-cholesta-5,7-dien-3 beta-ol.
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The biosynthesis of cholesta-8,14-dien-3beta-ol by Chang human liver cells.
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Total enzymic synthesis of cholesterol from 4,4,14 alpha-trimethyl-5 alpha-cholesta-8,24-dien-3 beta-ol. Solubilization, resolution, and reconstitution of delta 7-sterol 5-desaturase.
December 1982, The Journal of biological chemistry,
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Concerning the structure of 3 beta-benzoyloxy-5 beta-cholesta-8,14-diene, a major byproduct in the chemical synthesis of 5 alpha-cholest-8(14)-en-3 beta-ol-15-one.
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