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It has been claimed that lysis time methods may be inappropriate as measures of fibrinolytic activity on the grounds that they are largely determined by plasma fibrinogen levels. The dilute blood clot lysis time (DBCLT) has therefore been measured in 103 subjects; fibrinolytic activity (expressed as 100/DBCLT) has been compared with the fibrin plate area (FPA) lysed by the euglobulin fraction, the latter method being, of course, virtually independent of plasma fibrinogen. Plasma fibrinogen levels have also been measured; they ranged from 167 to 416 mg%. Results have been analysed by the technique of multiple regression. The incorporation of plasma fibrinogen levels in the regression equation relating 100/DBCLT to FPA does not result in a significant increase in the proportion of the variance in 100/DBCLT that can be explained. It is concluded that there is no evidence that DBCLT is influenced by plasma fibrinogen levels within the physiological range.
R Chakrabarti, and
W R North, and
T W Meade
January 1977,
Current medical research and opinion,
R Chakrabarti, and
W R North, and
T W Meade
February 1977,
The Journal of the Association of Physicians of India,
R Chakrabarti, and
W R North, and
T W Meade
February 1984,
Sheng zhi yu bi yun = Reproduction and contraception,
R Chakrabarti, and
W R North, and
T W Meade
January 1974,
Clinical nephrology,
R Chakrabarti, and
W R North, and
T W Meade
January 2002,
Current medical research and opinion,
R Chakrabarti, and
W R North, and
T W Meade
December 1961,
Scottish medical journal,
R Chakrabarti, and
W R North, and
T W Meade
January 1981,
Nauchnye doklady vysshei shkoly. Biologicheskie nauki,
R Chakrabarti, and
W R North, and
T W Meade
May 1981,
The Journal of the Association of Physicians of India,
R Chakrabarti, and
W R North, and
T W Meade
February 1967,
Akusherstvo i ginekologiia,
R Chakrabarti, and
W R North, and
T W Meade
January 1974,
Acta physiologica Polonica,
