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A new approach for measuring blood flow in bone is presented. It consists of the local injection of 133Xe into the proximal femur of adult beagles and the external measurement of isotope washout curves. The curves were analyzed using a two-compartment exponential model. The half-times for the tracer washout from the fast and slow compartment were 3.34 +/- 0.48 min and 33.6 +/- 11.7 min (mean +/- 1 S.D.) respectively. Blood flow was calculated using a measured blood to bone partition coefficient of 1.55 ml/g. The mean blood perfusion in proximal femur of the dog was 10.8 +/- 4.3 ml/100 g/min (mean +/- 1 S.D.). This value agrees well with most estimates of bone circulation. Due to rapid disappearance of 133Xe the method is easy to repeat and is thus suitable for physiological studies of local blood flow in bones.
T Lahtinen, and
E M Alhava, and
M Hakumäki, and
J Jääskeläinen, and
A Väänänen, and
P Karjalainen
June 1974,
Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova,
T Lahtinen, and
E M Alhava, and
M Hakumäki, and
J Jääskeläinen, and
A Väänänen, and
P Karjalainen
April 1974,
Pflugers Archiv : European journal of physiology,
T Lahtinen, and
E M Alhava, and
M Hakumäki, and
J Jääskeläinen, and
A Väänänen, and
P Karjalainen
June 1990,
Acta physiologica Scandinavica,
T Lahtinen, and
E M Alhava, and
M Hakumäki, and
J Jääskeläinen, and
A Väänänen, and
P Karjalainen
January 1977,
Acta neurologica Scandinavica. Supplementum,
T Lahtinen, and
E M Alhava, and
M Hakumäki, and
J Jääskeläinen, and
A Väänänen, and
P Karjalainen
January 1979,
Neoplasma,
T Lahtinen, and
E M Alhava, and
M Hakumäki, and
J Jääskeläinen, and
A Väänänen, and
P Karjalainen
June 1985,
Zhonghua yi xue za zhi,
T Lahtinen, and
E M Alhava, and
M Hakumäki, and
J Jääskeläinen, and
A Väänänen, and
P Karjalainen
January 1977,
Cor et vasa,
T Lahtinen, and
E M Alhava, and
M Hakumäki, and
J Jääskeläinen, and
A Väänänen, and
P Karjalainen
June 1986,
Experimental and clinical endocrinology,
T Lahtinen, and
E M Alhava, and
M Hakumäki, and
J Jääskeläinen, and
A Väänänen, and
P Karjalainen
September 1983,
Sbornik lekarsky,
T Lahtinen, and
E M Alhava, and
M Hakumäki, and
J Jääskeläinen, and
A Väänänen, and
P Karjalainen
May 1979,
The American journal of physiology,
