Regulation of the biosynthesis and interconversion of purine nucleotides.
1965
B Magasanik
UI
MeSH Term
Description
Entries
D009711
Nucleotides
The monomeric units from which DNA or RNA polymers are constructed. They consist of a purine or pyrimidine base, a pentose sugar, and a phosphate group. (From King & Stansfield, A Dictionary of Genetics, 4th ed)
Nucleotide
D011687
Purines
A series of heterocyclic compounds that are variously substituted in nature and are known also as purine bases. They include ADENINE and GUANINE, constituents of nucleic acids, as well as many alkaloids such as CAFFEINE and THEOPHYLLINE. Uric acid is the metabolic end product of purine metabolism.
D004794
Enzyme Repression
The interference in synthesis of an enzyme due to the elevated level of an effector substance, usually a metabolite, whose presence would cause depression of the gene responsible for enzyme synthesis.
Repression, Enzyme
D005246
Feedback
A mechanism of communication within a system in that the input signal generates an output response which returns to influence the continued activity or productivity of that system.