-transparent.png){kind=logo}
1. When a species of Achromobacter grew with beta-phenylpropionate as carbon source, 2-hydroxy-beta-phenylpropionate and 2,3-dihydroxy-beta-phenylpropionate appeared in the growth medium. The concentrations of these compounds were maximal during exponential growth. 2. The cells contained an oxygenase that required Fe(2+) ions and cleaved the benzene nucleus between the adjacent carbon atoms that bear the side chain and one hydroxyl group of 2,3-dihydroxy-beta-phenylpropionate. 3. The ring-fission product, formed with the consumption of 1mol. of oxygen/mol. of substrate, was isolated and a chemical structure assigned. Sephadex-treated cell extracts converted 1mol. of this compound into 1mol. of 4-hydroxy-2-oxovalerate without oxygen consumption; succinic acid was also formed. 4. When Mn(2+) ions or Mg(2+) ions were added, dialysed extracts converted 4-hydroxy-2-oxovalerate into pyruvate and acetaldehyde, but the reaction did not proceed to completion.
S Dagley, and
P J Chapman, and
D T Gibson
December 1979,
Zeitschrift fur Naturforschung. Section C, Biosciences,
S Dagley, and
P J Chapman, and
D T Gibson
January 1956,
Bollettino dell'Istituto sieroterapico milanese,
S Dagley, and
P J Chapman, and
D T Gibson
August 1959,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
S Dagley, and
P J Chapman, and
D T Gibson
January 1983,
European journal of cell biology,
S Dagley, and
P J Chapman, and
D T Gibson
January 1987,
Drug metabolism and disposition: the biological fate of chemicals,
S Dagley, and
P J Chapman, and
D T Gibson
January 1979,
Zeitschrift fur Naturforschung. Section C, Biosciences,
S Dagley, and
P J Chapman, and
D T Gibson
January 1987,
Pharmacology & therapeutics,
S Dagley, and
P J Chapman, and
D T Gibson
January 1968,
Farmakologiia i toksikologiia,
S Dagley, and
P J Chapman, and
D T Gibson
January 1987,
Drug metabolism and disposition: the biological fate of chemicals,
S Dagley, and
P J Chapman, and
D T Gibson
July 1964,
Biochemische Zeitschrift,
