[Effect of prolonged weightlessness on protein metabolism in rat red and white skeletal muscles]. 1977

V A Kazarian, and E A Rapoport, and L A Goncharova, and S Ia Bulycheva

With the aid of C14-leucine incorporation into proteins the protein synthesis in the red (m. soleus) and white (m. extensor dig. longus) skeletal muscles of flight and synchronous rats from the Cosmos-605 experiment was investigated. On the 2nd postflight day the total synthesis of proteins (as calculated per whole muscle) in the red muscle of flight rats remained unaltered. Therefore, distinct atrophy of this muscle that was seen only in flight rats can be attributed to increased degradation of proteins. On the 2nd postflight day the white muscle of both flight and synchronous rats showed moderate atrophy, not only increased protein degradation but also inhibited protein synthesis contributes to this.

UI MeSH Term Description Entries
D008297 Male Males
D009124 Muscle Proteins The protein constituents of muscle, the major ones being ACTINS and MYOSINS. More than a dozen accessory proteins exist including TROPONIN; TROPOMYOSIN; and DYSTROPHIN. Muscle Protein,Protein, Muscle,Proteins, Muscle
D009132 Muscles Contractile tissue that produces movement in animals. Muscle Tissue,Muscle,Muscle Tissues,Tissue, Muscle,Tissues, Muscle
D000205 Actomyosin A protein complex of actin and MYOSINS occurring in muscle. It is the essential contractile substance of muscle.
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012519 Sarcoplasmic Reticulum A network of tubules and sacs in the cytoplasm of SKELETAL MUSCLE FIBERS that assist with muscle contraction and relaxation by releasing and storing calcium ions. Reticulum, Sarcoplasmic,Reticulums, Sarcoplasmic,Sarcoplasmic Reticulums
D013026 Space Flight Travel beyond the earth's atmosphere. Space Exploration,Space Travel,Spaceflight,Exploration, Space,Explorations, Space,Flight, Space,Flights, Space,Space Explorations,Space Flights,Space Travels,Spaceflights,Travel, Space,Travels, Space
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor
D014893 Weightlessness Condition in which no acceleration, whether due to gravity or any other force, can be detected by an observer within a system. It also means the absence of weight or the absence of the force of gravity acting on a body. Microgravity, gravitational force between 0 and 10 -6 g, is included here. (From NASA Thesaurus, 1988) Microgravity,Zero Gravity,Gravity, Zero
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus

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