The Reiter protein complement-fixation test using the Auto-Analyzer. 1966

V W Pugh, and R W Gaze

A method for the Reiter protein complement-fixation test using the Techncon AutoAnalyzer is described. Two hundred and fifty sera were tested, when six false-positive and nine false-negative results were obtained when compared with results obtained by the manual method. Deep freezing the sera before testing on the AutoAnalyzer increased the sensitivity so that in a further 250 sera tested no false-negative and two false-positive results were obtained when compared with the results obtained at the Venereal Diseases Reference Laboratory, London.

UI MeSH Term Description Entries
D003168 Complement Fixation Tests Serologic tests based on inactivation of complement by the antigen-antibody complex (stage 1). Binding of free complement can be visualized by addition of a second antigen-antibody system such as red cells and appropriate red cell antibody (hemolysin) requiring complement for its completion (stage 2). Failure of the red cells to lyse indicates that a specific antigen-antibody reaction has taken place in stage 1. If red cells lyse, free complement is present indicating no antigen-antibody reaction occurred in stage 1. Complement Absorption Test, Conglutinating,Conglutination Reaction,Conglutinating Complement Absorption Test,Complement Fixation Test,Conglutination Reactions,Fixation Test, Complement,Fixation Tests, Complement,Reaction, Conglutination,Reactions, Conglutination,Test, Complement Fixation,Tests, Complement Fixation
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001322 Autoanalysis Method of analyzing chemicals using automation. Autoanalyses
D013588 Syphilis Serodiagnosis Serologic tests for syphilis. Kahn Test,Wassermann Reaction,Serodiagnosis, Syphilis,Reaction, Wassermann,Serodiagnoses, Syphilis,Syphilis Serodiagnoses,Test, Kahn

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