Mode of action of neocarzinostatin: inhibition of DNA synthesis and degradation of DNA in Sarcina lutea.
1966
Y Ono, and
Y Watanabe, and
N Ishida
UI
MeSH Term
Description
Entries
D007930
Leucine
An essential branched-chain amino acid important for hemoglobin formation.
L-Leucine,Leucine, L-Isomer,L-Isomer Leucine,Leucine, L Isomer
D008937
Mitomycins
A group of methylazirinopyrroloindolediones obtained from certain Streptomyces strains. They are very toxic antibiotics used as ANTINEOPLASTIC AGENTS in some solid tumors. PORFIROMYCIN and MITOMYCIN are the most useful members of the group.
D010455
Peptides
Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are considered to be larger versions of peptides that can form into complex structures such as ENZYMES and RECEPTORS.
Peptide,Polypeptide,Polypeptides
D004269
DNA, Bacterial
Deoxyribonucleic acid that makes up the genetic material of bacteria.
Bacterial DNA
D000903
Antibiotics, Antineoplastic
Chemical substances, produced by microorganisms, inhibiting or preventing the proliferation of neoplasms.
A genus of gram-positive, anaerobic bacteria whose organisms divide in three perpendicular planes and occur in packets of eight or more cells. It has been isolated from soil, grains, and clinical specimens.
D013936
Thymidine
A nucleoside in which THYMINE is linked to DEOXYRIBOSE.