BIOMAT Database Logo BIOMAT Database Logo

Effect of some monoamine oxidase inhibitors on deamination of biogenic monoamines by rat liver mitochondrial monoamine oxidase. 1966

V Z Gorkin, and L I Gridneva, and L B Klyashtorin, and I V Veryovkina, and I Vina

UI MeSH Term Description Entries
D007520 Isocarboxazid An MAO inhibitor that is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in the treatment of panic disorder and the phobic disorders. (From AMA, Drug Evaluations Annual, 1994, p311)
D008099 Liver A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances. Livers
D008928 Mitochondria Semiautonomous, self-reproducing organelles that occur in the cytoplasm of all cells of most, but not all, eukaryotes. Each mitochondrion is surrounded by a double limiting membrane. The inner membrane is highly invaginated, and its projections are called cristae. Mitochondria are the sites of the reactions of oxidative phosphorylation, which result in the formation of ATP. They contain distinctive RIBOSOMES, transfer RNAs (RNA, TRANSFER); AMINO ACYL T RNA SYNTHETASES; and elongation and termination factors. Mitochondria depend upon genes within the nucleus of the cells in which they reside for many essential messenger RNAs (RNA, MESSENGER). Mitochondria are believed to have arisen from aerobic bacteria that established a symbiotic relationship with primitive protoeukaryotes. (King & Stansfield, A Dictionary of Genetics, 4th ed) Mitochondrial Contraction,Mitochondrion,Contraction, Mitochondrial,Contractions, Mitochondrial,Mitochondrial Contractions
D008995 Monoamine Oxidase An enzyme that catalyzes the oxidative deamination of naturally occurring monoamines. It is a flavin-containing enzyme that is localized in mitochondrial membranes, whether in nerve terminals, the liver, or other organs. Monoamine oxidase is important in regulating the metabolic degradation of catecholamines and serotonin in neural or target tissues. Hepatic monoamine oxidase has a crucial defensive role in inactivating circulating monoamines or those, such as tyramine, that originate in the gut and are absorbed into the portal circulation. (From Goodman and Gilman's, The Pharmacological Basis of Therapeutics, 8th ed, p415) EC 1.4.3.4. Amine Oxidase (Flavin-Containing),MAO,MAO-A,MAO-B,Monoamine Oxidase A,Monoamine Oxidase B,Type A Monoamine Oxidase,Type B Monoamine Oxidase,Tyramine Oxidase,MAO A,MAO B,Oxidase, Monoamine,Oxidase, Tyramine
D010293 Pargyline A monoamine oxidase inhibitor with antihypertensive properties. Pargyline Hydrochloride,Hydrochloride, Pargyline
D010624 Phenelzine One of the MONOAMINE OXIDASE INHIBITORS used to treat DEPRESSION; PHOBIC DISORDERS; and PANIC. Fenelzin,2-Phenethylhydrazine,Nardelzine,Nardil,Phenelzine Sulfate,Phenethylhydrazine,beta-Phenylethylhydrazine,2 Phenethylhydrazine,Sulfate, Phenelzine,beta Phenylethylhydrazine
D011804 Quinolines
D003956 Dialysis A process of selective diffusion through a membrane. It is usually used to separate low-molecular-weight solutes which diffuse through the membrane from the colloidal and high-molecular-weight solutes which do not. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Dialyses
D004298 Dopamine One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action. Hydroxytyramine,3,4-Dihydroxyphenethylamine,4-(2-Aminoethyl)-1,2-benzenediol,Dopamine Hydrochloride,Intropin,3,4 Dihydroxyphenethylamine,Hydrochloride, Dopamine
D000470 Alkaloids Organic nitrogenous bases. Many alkaloids of medical importance occur in the animal and vegetable kingdoms, and some have been synthesized. (Grant & Hackh's Chemical Dictionary, 5th ed) Alkaloid,Plant Alkaloid,Plant Alkaloids,Alkaloid, Plant,Alkaloids, Plant

Related Publications

V Z Gorkin, and L I Gridneva, and L B Klyashtorin, and I V Veryovkina, and I Vina
On the selective inhibition by some monoamine oxidase inhibitors of deamination of biogenic monoamines in vivo.
June 1968, Biochemical pharmacology,
V Z Gorkin, and L I Gridneva, and L B Klyashtorin, and I V Veryovkina, and I Vina
[Deamination of biogenic amines by mitochondrial monoamine oxidase in human fetal liver].
January 1973, Zhurnal evoliutsionnoi biokhimii i fiziologii,
V Z Gorkin, and L I Gridneva, and L B Klyashtorin, and I V Veryovkina, and I Vina
[Oxidative deamination data on biogenic monoamines in the mitochondrial fraction of rat brain and liver].
April 1981, Gigiena truda i professional'nye zabolevaniia,
V Z Gorkin, and L I Gridneva, and L B Klyashtorin, and I V Veryovkina, and I Vina
Effect of selective monoamine oxidase inhibitors on rat brain mitochondrial monoamine oxidase during hyperbaric oxygenation.
January 1977, Communications in psychopharmacology,
V Z Gorkin, and L I Gridneva, and L B Klyashtorin, and I V Veryovkina, and I Vina
Monoamine oxidase activities towards biogenic monoamines in several regions of rat brain.
January 1975, Journal of neurochemistry,
V Z Gorkin, and L I Gridneva, and L B Klyashtorin, and I V Veryovkina, and I Vina
[Mechanism of inhibition by chlorgyline and deprenyl of tyramine deamination by mitochondrial monoamine oxidase of rat liver].
October 1980, Biokhimiia (Moscow, Russia),
V Z Gorkin, and L I Gridneva, and L B Klyashtorin, and I V Veryovkina, and I Vina
The effect of tris buffers on rat liver mitochondrial monoamine oxidase.
July 1977, The Journal of pharmacy and pharmacology,
V Z Gorkin, and L I Gridneva, and L B Klyashtorin, and I V Veryovkina, and I Vina
[Effect of some derivatives of piperidine, piperazine and related compounds on deamination of serotonin, tyramine and benzylamine by pig liver mitochondrial monoamine oxidase].
January 1983, Biokhimiia (Moscow, Russia),
V Z Gorkin, and L I Gridneva, and L B Klyashtorin, and I V Veryovkina, and I Vina
[Deamination of some biogenic monoamines and succinate dehydrogenase activity in mitochondria].
January 1971, Voprosy meditsinskoi khimii,
V Z Gorkin, and L I Gridneva, and L B Klyashtorin, and I V Veryovkina, and I Vina
Age-related changes in brain biogenic monoamines and monoamine oxidase.
January 1987, General pharmacology,
Copied contents to your clipboard!