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[Synthesis of a decapeptide derivative with the 21-30 sequence from the B-chain of human insulin]. 1966

J Meienhofer

UI MeSH Term Description Entries
D007328 Insulin A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1). Iletin,Insulin A Chain,Insulin B Chain,Insulin, Regular,Novolin,Sodium Insulin,Soluble Insulin,Chain, Insulin B,Insulin, Sodium,Insulin, Soluble,Regular Insulin
D010455 Peptides Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are considered to be larger versions of peptides that can form into complex structures such as ENZYMES and RECEPTORS. Peptide,Polypeptide,Polypeptides
D002625 Chemistry, Organic The study of the structure, preparation, properties, and reactions of carbon compounds. (McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed) Organic Chemistry
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D055601 Organic Chemistry Phenomena The conformation, properties, reaction processes, and the properties of the reactions of organic carbon compounds. Organic Chemistry Concepts,Organic Chemistry Processes,Organic Chemistry Phenomenon,Organic Chemistry Process,Chemistry Process, Organic,Chemistry Processes, Organic,Concept, Organic Chemistry,Concepts, Organic Chemistry,Organic Chemistry Concept,Phenomena, Organic Chemistry,Phenomenon, Organic Chemistry,Process, Organic Chemistry,Processes, Organic Chemistry

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[NEW SYNTHESIS OF INSULIN SEQUENCE B 21-30].
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Synthesis of protected decapeptide (B21--30) of human insulin.
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[Synthesis of a pentapeptide derivative with the C-terminal sequence A 17-21 of the insulin A-chain].
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Spontaneous dimer states of the Aβ(21-30) decapeptide.
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