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The molecular weight distribution of the components of giant hornet (Vespa orientalis) venom was studied, using gel-filtration on a column with Sephadex G-50. The effects of the venom and its constituent fractions on the permeability and stability of artificial bilayer phospholipid membranes, potassium ions release from the erythrocytes and mitochondrial oxidative phosphorylation parameters, as well as on the activity and stability of polyenzymic systems of the mitochondrial respiratroy chain, were studied. The data obtained suggest that the high molecular weight fractions contain phospholipases, whose activities are much higher than those of presently known venoms. Despite the fact that the hemolytic effect is typical for two low molecular weight fractions, no fractions possessing high activity of bee venom of the melitin type were found.
M U Tuĭchibaev, and
F A Muksimov, and
N Akhmedova, and
A V Shkinev, and
U Z Mirkhodzhaev, and
U Z Muratova, and
K T Almatov, and
M M Rakhimov, and
B A Ashmukhamedov
January 1972,
Toxicon : official journal of the International Society on Toxinology,
M U Tuĭchibaev, and
F A Muksimov, and
N Akhmedova, and
A V Shkinev, and
U Z Mirkhodzhaev, and
U Z Muratova, and
K T Almatov, and
M M Rakhimov, and
B A Ashmukhamedov
January 1989,
Advances in experimental medicine and biology,
M U Tuĭchibaev, and
F A Muksimov, and
N Akhmedova, and
A V Shkinev, and
U Z Mirkhodzhaev, and
U Z Muratova, and
K T Almatov, and
M M Rakhimov, and
B A Ashmukhamedov
August 1975,
Toxicon : official journal of the International Society on Toxinology,
M U Tuĭchibaev, and
F A Muksimov, and
N Akhmedova, and
A V Shkinev, and
U Z Mirkhodzhaev, and
U Z Muratova, and
K T Almatov, and
M M Rakhimov, and
B A Ashmukhamedov
January 1990,
International archives of allergy and applied immunology,
M U Tuĭchibaev, and
F A Muksimov, and
N Akhmedova, and
A V Shkinev, and
U Z Mirkhodzhaev, and
U Z Muratova, and
K T Almatov, and
M M Rakhimov, and
B A Ashmukhamedov
May 1999,
Toxicon : official journal of the International Society on Toxinology,
M U Tuĭchibaev, and
F A Muksimov, and
N Akhmedova, and
A V Shkinev, and
U Z Mirkhodzhaev, and
U Z Muratova, and
K T Almatov, and
M M Rakhimov, and
B A Ashmukhamedov
January 1976,
Toxicon : official journal of the International Society on Toxinology,
M U Tuĭchibaev, and
F A Muksimov, and
N Akhmedova, and
A V Shkinev, and
U Z Mirkhodzhaev, and
U Z Muratova, and
K T Almatov, and
M M Rakhimov, and
B A Ashmukhamedov
January 2014,
The journal of venomous animals and toxins including tropical diseases,
M U Tuĭchibaev, and
F A Muksimov, and
N Akhmedova, and
A V Shkinev, and
U Z Mirkhodzhaev, and
U Z Muratova, and
K T Almatov, and
M M Rakhimov, and
B A Ashmukhamedov
December 1976,
Experientia,
M U Tuĭchibaev, and
F A Muksimov, and
N Akhmedova, and
A V Shkinev, and
U Z Mirkhodzhaev, and
U Z Muratova, and
K T Almatov, and
M M Rakhimov, and
B A Ashmukhamedov
May 1979,
Experientia,
M U Tuĭchibaev, and
F A Muksimov, and
N Akhmedova, and
A V Shkinev, and
U Z Mirkhodzhaev, and
U Z Muratova, and
K T Almatov, and
M M Rakhimov, and
B A Ashmukhamedov
January 1990,
Journal of clinical laboratory analysis,
