Biomaterial Database

A large open multicentre trial of clomipramine (Anafranil) in the management of phobic disorders. 1977

G Beaumont

In a large, open, multicentre trial, conducted in general practice, 765 patients suffering from agoraphobia or social phobias were treated with clomipramine (Anafranil, Geigy Pharmaceuticals). Four hundred and eight patients completed a twelve-week course of treatment. Of 285 withdrawals, 139 were due to side-effects. Good results were obtained on all measures of phobias in those patients who completed the study, the improvements being of the order of 70-80%, and over 50% of patients being symptom-free.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008393	Marriage	The social institution involving legal and/or religious sanction whereby individuals are joined together.	Marital Relationship,Arranged Marriage,Commonlaw Marriage,Consensual Union,Consummation of Marriage,Dowry,Husband-Wife Comparisons,Intermarriage,Marriage Age,Marriage Duration,Marriage Patterns,Marriage Postponement,Mate Selection,Multiple Marriages,Nuptiality,Polygamy,Polygyny,Remarriage,Same-Sex Marriage,Age, Marriage,Ages, Marriage,Arranged Marriages,Commonlaw Marriages,Comparison, Husband-Wife,Comparisons, Husband-Wife,Consensual Unions,Dowries,Duration, Marriage,Husband Wife Comparisons,Husband-Wife Comparison,Intermarriages,Marital Relationships,Marriage Ages,Marriage Consummation,Marriage Consummations,Marriage Pattern,Marriage Postponements,Marriage, Arranged,Marriage, Commonlaw,Marriage, Same-Sex,Marriages,Marriages, Arranged,Marriages, Commonlaw,Marriages, Multiple,Marriages, Same-Sex,Mate Selections,Postponement, Marriage,Postponements, Marriage,Relationship, Marital,Relationships, Marital,Remarriages,Same Sex Marriage,Same-Sex Marriages,Selection, Mate,Selections, Mate,Union, Consensual,Unions, Consensual
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D010352	Patient Dropouts	Discontinuance of care received by patient(s) due to reasons other than full recovery from the disease.	Dropout, Patient,Dropouts, Patient,Patient Dropout
D010698	Phobic Disorders	Anxiety disorders in which the essential feature is persistent and irrational fear of a specific object, activity, or situation that the individual feels compelled to avoid. The individual recognizes the fear as excessive or unreasonable.	Claustrophobia,Neuroses, Phobic,Phobia, School,Phobias,Phobic Neuroses,Scolionophobia,Disorder, Phobic,Phobia,Phobic Disorder,School Phobia
D002997	Clomipramine	A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.	Chlorimipramine,Anafranil,Chlomipramine,Clomipramine Hydrochloride,Clomipramine Maleate (1:1),Clomipramine Monohydrochloride,Hydiphen,Hydrochloride, Clomipramine,Monohydrochloride, Clomipramine
D003984	Dibenzazepines	Compounds with two BENZENE rings fused to AZEPINES.
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths