Biomaterial Database

The forced end-expiratory flow rate in chloromethyl ether workers. 1977

W Weiss

Spirograms were made in 103 chemical workers, 72 of whom had been exposed for years to chloromethyl ethers to various degrees. The end-expiratory flow rate was below 60% of predicted in one-third of exposed men compared to only 3% of unexposed men. Smoking was a confounding factor. In 49 current cigarette smokers consuming less than one pack per day, the data suggested a dose-response relationship between chemical exposure and the frequency of low end-expiratory flow rate.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008738	Methyl Ethers	A group of compounds that contain the general formula R-OCH3.	Ethers, Methyl
D009787	Occupational Medicine	Medical specialty concerned with the promotion and maintenance of the physical and mental health of employees in occupational settings.	Industrial Medicine,Medicine, Industrial,Medicine, Occupational
D001725	Bis(Chloromethyl) Ether	A substance that is an irritant to the eyes and respiratory tract and may be carcinogenic.	Chloromethyl Ether,Dichloromethyl Ether,Bis(Chloromethyl)Ether,Ether, Chloromethyl,Ether, Dichloromethyl
D002617	Chemical Industry	The aggregate enterprise of manufacturing and technically producing chemicals. (From Random House Unabridged Dictionary, 2d ed)	Industry, Chemical,Chemical Industries,Industries, Chemical
D004305	Dose-Response Relationship, Drug	The relationship between the dose of an administered drug and the response of the organism to the drug.	Dose Response Relationship, Drug,Dose-Response Relationships, Drug,Drug Dose-Response Relationship,Drug Dose-Response Relationships,Relationship, Drug Dose-Response,Relationships, Drug Dose-Response
D004781	Environmental Exposure	The exposure to potentially harmful chemical, physical, or biological agents in the environment or to environmental factors that may include ionizing radiation, pathogenic organisms, or toxic chemicals.	Exposure, Environmental,Environmental Exposures,Exposures, Environmental
D005540	Forced Expiratory Flow Rates	The rate of airflow measured during a FORCED VITAL CAPACITY determination.	Expiratory Forced Flow Rates,Flow Rates, Expiratory Forced,Flow Rates, Forced Expiratory
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012907	Smoking	Willful or deliberate act of inhaling and exhaling SMOKE from burning substances or agents held by hand.	Smoking Behaviors,Smoking Habit,Behavior, Smoking,Behaviors, Smoking,Habit, Smoking,Habits, Smoking,Smoking Behavior,Smoking Habits