Gentamicin disposition and tissue accumulation on multiple dosing.
1977
J J Schentag, and
W J Jusko, and
J W Vance, and
T J Cumbo, and
E Abrutyn, and
M DeLattre, and
L M Gerbracht
UI
MeSH Term
Description
Entries
D008875
Middle Aged
An adult aged 45 - 64 years.
Middle Age
D005839
Gentamicins
A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368
Aged
A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.
Elderly
D014018
Tissue Distribution
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.