A specific radio-immunoassay procedure for plasma clomipramine.
1977
G F Read, and
D Riad-Fahmy, and
R F Walker
UI
MeSH Term
Description
Entries
D008297
Male
Males
D008875
Middle Aged
An adult aged 45 - 64 years.
Middle Age
D011863
Radioimmunoassay
Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation.
Radioimmunoassays
D002997
Clomipramine
A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.