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A schedule for the prevention of tetanus in the injured, which has been in operation in the emergency department of a large hospital for over two years, is proposed. For the majority of nonimmunized persons, it is recommended that a dose of toxoid and 50 units tetanus immune globulin (human) (TIGH) be given, in separate sites, to be followed later by additional doses of toxoid for the completion of active immunization. Combined active-passive immunization with tetanus toxoid and 50 units TIGH gives a low level of passive immunity and stimulates early onset of active immunization. In combined active-passive immunization, adsorbed tetanus toxoid produced a significantly higher response than the fluid toxoid. The injection of 400 units TIGH somewhat suppressed the induction of immunity following the first dose of AlPO(4)-tetanus toxoid.
L J Mahoney, and
M A Aprile, and
P J Moloney
April 1976,
Zeitschrift fur Immunitatsforschung, experimentelle und klinische Immunologie,
L J Mahoney, and
M A Aprile, and
P J Moloney
July 1965,
The Medical journal of Australia,
L J Mahoney, and
M A Aprile, and
P J Moloney
September 1964,
Orvosi hetilap,
L J Mahoney, and
M A Aprile, and
P J Moloney
January 1952,
Zentralblatt fur Chirurgie,
L J Mahoney, and
M A Aprile, and
P J Moloney
January 1986,
Medicinski pregled,
L J Mahoney, and
M A Aprile, and
P J Moloney
April 1966,
Connecticut medicine,
L J Mahoney, and
M A Aprile, and
P J Moloney
January 1918,
Medical bulletin (Paris, France),
L J Mahoney, and
M A Aprile, and
P J Moloney
September 1978,
Immunology,
L J Mahoney, and
M A Aprile, and
P J Moloney
November 1964,
The New England journal of medicine,
L J Mahoney, and
M A Aprile, and
P J Moloney
March 1948,
The Journal of hygiene,
