-transparent.png){kind=logo}
Haemolytic anaemia in a Black South African child was found to be associated with reduced glucosephosphate isomerase activity in the red cells. Apart from the haemolytic anaemia, there was no other clinical evidence of dysfunction. Family studies pointed to an autosomal recessive mode of inheritance, with the symptomatic homozygous propositus having a marked enzyme deficiency and the asymptomatic heterozygotes showing intermediate levels of activity. Biochemical characterization showed that, apart from being thermolabile, the electrophoretic mobility and the kinetic properites of the variant enzyme were similar to those of the normal wild type.
Related Publications
E Cayanis, and
G K Penfold, and
I Freiman, and
L G MacDougall
August 1977,
British journal of haematology,
E Cayanis, and
G K Penfold, and
I Freiman, and
L G MacDougall
June 1974,
Annals of internal medicine,
E Cayanis, and
G K Penfold, and
I Freiman, and
L G MacDougall
January 1978,
Scandinavian journal of haematology,
E Cayanis, and
G K Penfold, and
I Freiman, and
L G MacDougall
February 1983,
Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society,
E Cayanis, and
G K Penfold, and
I Freiman, and
L G MacDougall
December 1997,
Blood cells, molecules & diseases,
E Cayanis, and
G K Penfold, and
I Freiman, and
L G MacDougall
October 1993,
Annals of hematology,
E Cayanis, and
G K Penfold, and
I Freiman, and
L G MacDougall
December 1975,
Clinica chimica acta; international journal of clinical chemistry,
E Cayanis, and
G K Penfold, and
I Freiman, and
L G MacDougall
July 1977,
Clinica chimica acta; international journal of clinical chemistry,
E Cayanis, and
G K Penfold, and
I Freiman, and
L G MacDougall
November 1985,
European journal of pediatrics,
E Cayanis, and
G K Penfold, and
I Freiman, and
L G MacDougall
January 1990,
Acta haematologica,
