1-amino-4-aryl-4-piperidinols as potential antidepressants. 1967

N J Harper, and C W Hussey, and M E Peel, and A C Ritchie, and J M Waring

UI MeSH Term Description Entries
D007099 Imipramine The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group. Imidobenzyle,Imizin,4,4'-Methylenebis(3-hydroxy-2-naphthoic acid)-3-(10,11-dihydro-5H-dibenzo(b,f)azepin-5-yl)-N,N-dimethyl-1-propanamine (1:2),Imipramine Hydrochloride,Imipramine Monohydrochloride,Imipramine Pamoate,Janimine,Melipramine,Norchlorimipramine,Pryleugan,Tofranil
D010880 Piperidines A family of hexahydropyridines.
D000588 Amines A group of compounds derived from ammonia by substituting organic radicals for the hydrogens. (From Grant & Hackh's Chemical Dictionary, 5th ed) Amine
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000928 Antidepressive Agents Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems. Antidepressant,Antidepressant Drug,Antidepressant Medication,Antidepressants,Antidepressive Agent,Thymoanaleptic,Thymoanaleptics,Thymoleptic,Thymoleptics,Antidepressant Drugs,Agent, Antidepressive,Drug, Antidepressant,Medication, Antidepressant
D051379 Mice The common name for the genus Mus. Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus

Related Publications

N J Harper, and C W Hussey, and M E Peel, and A C Ritchie, and J M Waring
May 2010, Archiv der Pharmazie,
N J Harper, and C W Hussey, and M E Peel, and A C Ritchie, and J M Waring
May 2001, Die Pharmazie,
N J Harper, and C W Hussey, and M E Peel, and A C Ritchie, and J M Waring
January 2010, Zeitschrift fur Naturforschung. C, Journal of biosciences,
N J Harper, and C W Hussey, and M E Peel, and A C Ritchie, and J M Waring
October 2014, Molecules (Basel, Switzerland),
N J Harper, and C W Hussey, and M E Peel, and A C Ritchie, and J M Waring
November 2010, Bioorganic & medicinal chemistry letters,
N J Harper, and C W Hussey, and M E Peel, and A C Ritchie, and J M Waring
July 1978, Journal of medicinal chemistry,
N J Harper, and C W Hussey, and M E Peel, and A C Ritchie, and J M Waring
January 1981, Journal of medicinal chemistry,
N J Harper, and C W Hussey, and M E Peel, and A C Ritchie, and J M Waring
November 1964, Journal of medicinal chemistry,
N J Harper, and C W Hussey, and M E Peel, and A C Ritchie, and J M Waring
January 2001, Annual review of pharmacology and toxicology,
N J Harper, and C W Hussey, and M E Peel, and A C Ritchie, and J M Waring
March 2014, Bioorganic & medicinal chemistry letters,
Copied contents to your clipboard!