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A series of teratocarcinoma-thymus hybrid cells (PCT hybrids), which had been shown previously to give rise to multidifferentiated tumors and hence to be pluripotent, was tested to see whether these cells resembled their embryonal carcinoma parent in other ways as well. PCT hybrid cells looked like embryonal carcinoma parent in other ways as well. PCT hybrid cells looked like embryonal carcinoma cells by phase contrast and electron microscopy, have high levels of alkaline phosphatase, and fail to express Thy 1 alloantigen (which is present on thymocyte parental cells, but not on embryonal carcinoma cells). PCT hybrids do, however, exhibit H2 antigens, which are present only at very low levels, if at all, on embryonal carcinoma cells.
R A Miller, and
F H Ruddle
January 1983,
Somatic cell genetics,
R A Miller, and
F H Ruddle
January 1979,
Haematology and blood transfusion,
R A Miller, and
F H Ruddle
October 1979,
Journal of cellular physiology,
R A Miller, and
F H Ruddle
May 1984,
Molecular and cellular biology,
R A Miller, and
F H Ruddle
December 1978,
Cell,
R A Miller, and
F H Ruddle
September 1984,
Experimental cell research,
R A Miller, and
F H Ruddle
February 1972,
Nature: New biology,
R A Miller, and
F H Ruddle
January 1971,
The Soviet journal of developmental biology,
R A Miller, and
F H Ruddle
June 1985,
Shi yan sheng wu xue bao,
