Efficacy of albendazole against inhibited early fourth stage larvae of Ostertagia ostertagi. 1977

J C Williams, and J W Knox, and D Sheehan, and R H Fuselier

Twelve untreated controls and 12 treated beef yearling steers were used in trials of albendazole (Smith Kline Animal Health Products) at 7.5 mg per kg (oral drench) against natural infections of inhibited fourth stage larvae of Ostertagia ostertagi. Albendazole had an efficacy of 83.8 per cent in removal of inhibited larvae. The mean number of inhibited larvae in untreated controls was 48.9 per cent. Efficacy against developing stages and adults of O ostertagi was 92.8 and 99.7 per cent, respectively. Efficacy against other worm genera in the abomasum, primarily thaemonchus and Cooperia adults, was 99.4 per cent. No signs of toxicity were observed following administration of albendazole. Some aspects of inhibition of O ostertagi in cattle in the USA are reviewed.

UI MeSH Term Description Entries
D008297 Male Males
D010029 Ostertagiasis A disease of herbivorous mammals, particularly cattle and sheep, caused by stomach worms of the genus OSTERTAGIA. Ostertagiases
D002417 Cattle Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor. Beef Cow,Bos grunniens,Bos indicus,Bos indicus Cattle,Bos taurus,Cow,Cow, Domestic,Dairy Cow,Holstein Cow,Indicine Cattle,Taurine Cattle,Taurus Cattle,Yak,Zebu,Beef Cows,Bos indicus Cattles,Cattle, Bos indicus,Cattle, Indicine,Cattle, Taurine,Cattle, Taurus,Cattles, Bos indicus,Cattles, Indicine,Cattles, Taurine,Cattles, Taurus,Cow, Beef,Cow, Dairy,Cow, Holstein,Cows,Dairy Cows,Domestic Cow,Domestic Cows,Indicine Cattles,Taurine Cattles,Taurus Cattles,Yaks,Zebus
D002418 Cattle Diseases Diseases of domestic cattle of the genus Bos. It includes diseases of cows, yaks, and zebus. Bovine Diseases,Bovine Disease,Cattle Disease,Disease, Bovine,Disease, Cattle,Diseases, Bovine,Diseases, Cattle
D000018 Abomasum The fourth stomach of ruminating animals. It is also called the "true" stomach. It is an elongated pear-shaped sac lying on the floor of the abdomen, on the right-hand side, and roughly between the seventh and twelfth ribs. It leads to the beginning of the small intestine. (From Black's Veterinary Dictionary, 17th ed) Abomasums
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000871 Anthelmintics Agents that kill parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal. Anthelmintic,Antihelmintic,Vermifuge,Vermifuges,Antihelmintics
D001562 Benzimidazoles Compounds with a BENZENE fused to IMIDAZOLES.
D014252 Trichostrongyloidiasis Infection by roundworms of the superfamily TRICHOSTRONGYLOIDEA, including the genera TRICHOSTRONGYLUS; OSTERTAGIA; Cooperia, HAEMONCHUS; Nematodirus, Hyostrongylus, and DICTYOCAULUS. Trichostrongyloidiases

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