Biomaterial Database

Effects of constant illumination on vision in the albino rat. 1977

D Birch, and G H Jacobs

The characteristics of photically-induced blinding in the albino rat were investigated with physiological (the electroretinogram--ERG) and behavioral (luminance discrimination) techniques. These indices were obtained both before and during exposure to constant illumination (2600 lux). In trast to previous results, the findings of this study indicate that both the amplitude of the ERG and the ability to discriminate test lights decline rapidly and at approximately the same rate following the onset of constant illumination. These results, in conjunction with others already in the literature, lead to the suggestion that the degree of correspondence between behavioral and other measures of photically-induced blinding is dependent on the rate of retinal degeneration.

UI	MeSH Term	Description	Entries
D008027	Light	That portion of the electromagnetic spectrum in the visible, ultraviolet, and infrared range.	Light, Visible,Photoradiation,Radiation, Visible,Visible Radiation,Photoradiations,Radiations, Visible,Visible Light,Visible Radiations
D008297	Male		Males
D009043	Motor Activity	Body movements of a human or an animal as a behavioral phenomenon.	Activities, Motor,Activity, Motor,Motor Activities
D012160	Retina	The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent.	Ora Serrata
D004192	Discrimination, Psychological	Differential response to different stimuli.	Discrimination, Psychology,Psychological Discrimination
D004596	Electroretinography	Recording of electric potentials in the retina after stimulation by light.	Electroretinographies
D000417	Albinism	General term for a number of inherited defects of amino acid metabolism in which there is a deficiency or absence of pigment in the eyes, skin, or hair.
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013577	Syndrome	A characteristic symptom complex.	Symptom Cluster,Cluster, Symptom,Clusters, Symptom,Symptom Clusters,Syndromes
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor