-transparent.png){kind=logo}
Intragastric administration of casein, oleic acid, or polyvinylpyrrolidone resulted in a marked increase in the pancreatic secretion of enzymes, and the administration of 0.03% sodium saccharin, at the concentration permitted in soft drinks, inhibited this increase with these substances. The stimulation of secretion of pancreatic juice-bile mixture by these substances was also inhibited by administration of sodium saccharin. Intravenous injection of CCK-PZ (cholecystokinin-pancreozymin) during inhibition by sodium saccharin, caused a rapid increase in amylase output, suggesting that sodium saccharin acts on the site(s) of CCK-PZ release to prevent its secretion even in the presence of a stimulant, but does not reduce the sensitivity of the pancreas to CCK-PZ. Sodium saccharin seemed to have an effect on secretin release similar to that on CCK-PZ release, judging from the results for the volume of juice-bile mixture.
M Kondoh, and
M Ohe, and
A Ono, and
H Hagihira
March 1995,
Scanning microscopy,
M Kondoh, and
M Ohe, and
A Ono, and
H Hagihira
December 1988,
Gastroenterologia Japonica,
M Kondoh, and
M Ohe, and
A Ono, and
H Hagihira
November 1974,
Gastroenterology,
M Kondoh, and
M Ohe, and
A Ono, and
H Hagihira
October 2007,
Regulatory peptides,
M Kondoh, and
M Ohe, and
A Ono, and
H Hagihira
December 1980,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
M Kondoh, and
M Ohe, and
A Ono, and
H Hagihira
October 1984,
Biochemical pharmacology,
M Kondoh, and
M Ohe, and
A Ono, and
H Hagihira
December 1989,
Regulatory peptides,
M Kondoh, and
M Ohe, and
A Ono, and
H Hagihira
October 1987,
Biochemical pharmacology,
M Kondoh, and
M Ohe, and
A Ono, and
H Hagihira
May 1977,
The American journal of digestive diseases,
M Kondoh, and
M Ohe, and
A Ono, and
H Hagihira
December 1992,
Revista espanola de fisiologia,
