-transparent.png){kind=logo}
Electron-dense round granules (ING) were found in the nuclei of fibroblastic cells of all the tumors examined by us (6 cases) and diagnosed clinically and histologically as nasopharyngeal angiofibroma (NPAF). The ING were consistently associated with this tumor and can be regarded as pathognomonic of NPAF. We studied at the ultrastructural level the composition of these particles using various cytochemical techniques. Enzymatic digestions carried out on thin sections as well as staining methods preferential or specific for nucleoproteins have revealed that ING represent tightly bound RNA-protein complexes and do not contain DNA. There are no data available that the ING takes part in the metabolism of NPAF fibroblastic cells.
A Topilko, and
A Zakrzewski, and
E Pichard, and
A Viron
September 1992,
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society,
A Topilko, and
A Zakrzewski, and
E Pichard, and
A Viron
March 1977,
Cancer,
A Topilko, and
A Zakrzewski, and
E Pichard, and
A Viron
August 1979,
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society,
A Topilko, and
A Zakrzewski, and
E Pichard, and
A Viron
January 1980,
Archives d'anatomie et de cytologie pathologiques,
A Topilko, and
A Zakrzewski, and
E Pichard, and
A Viron
January 1973,
Comptes rendus des seances de la Societe de biologie et de ses filiales,
A Topilko, and
A Zakrzewski, and
E Pichard, and
A Viron
June 1979,
Experimental parasitology,
A Topilko, and
A Zakrzewski, and
E Pichard, and
A Viron
July 1998,
Human pathology,
A Topilko, and
A Zakrzewski, and
E Pichard, and
A Viron
January 1988,
Journal of nematology,
A Topilko, and
A Zakrzewski, and
E Pichard, and
A Viron
April 1977,
Histochemistry,
A Topilko, and
A Zakrzewski, and
E Pichard, and
A Viron
January 1963,
Transactions - American Academy of Ophthalmology and Otolaryngology. American Academy of Ophthalmology and Otolaryngology,
