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Laboratory colonies of feral mice (Mus musculus domesticus) have been established with specific mouse mammary tumor virus (MuMTV) genotype, including colonies lacking any proviral DNA (ev-) or carrying only a single copy of MuMTV DNA (ev+). No evidence of a decline in reproductive capacity has been observed in the first 8 generations. Both the ev- and ev+ mice showed normal mammary gland development and the development of hyperplastic lesions in the older females. The mice were very resistant to spontaneous or chemically induced mammary tumors. However, the occurrence of 1 mammary tumor in an ev- mouse indicates that mammary neoplasias can occur in the absence of MuMTV DNA. The few tumors that do occur in the ev- mice provide a unique opportunity to study the neoplastic process in the absence of proviral DNA.
L J Faulkin, and
D J Mitchell, and
L J Young, and
D W Morris, and
R W Malone, and
R D Cardiff, and
M B Gardner
January 1981,
Cell,
L J Faulkin, and
D J Mitchell, and
L J Young, and
D W Morris, and
R W Malone, and
R D Cardiff, and
M B Gardner
March 1995,
European journal of immunology,
L J Faulkin, and
D J Mitchell, and
L J Young, and
D W Morris, and
R W Malone, and
R D Cardiff, and
M B Gardner
October 1987,
The Japanese journal of experimental medicine,
L J Faulkin, and
D J Mitchell, and
L J Young, and
D W Morris, and
R W Malone, and
R D Cardiff, and
M B Gardner
May 1986,
Journal of virology,
L J Faulkin, and
D J Mitchell, and
L J Young, and
D W Morris, and
R W Malone, and
R D Cardiff, and
M B Gardner
December 1963,
Gan,
L J Faulkin, and
D J Mitchell, and
L J Young, and
D W Morris, and
R W Malone, and
R D Cardiff, and
M B Gardner
February 1993,
Immunological reviews,
L J Faulkin, and
D J Mitchell, and
L J Young, and
D W Morris, and
R W Malone, and
R D Cardiff, and
M B Gardner
January 1987,
Journal of virology,
L J Faulkin, and
D J Mitchell, and
L J Young, and
D W Morris, and
R W Malone, and
R D Cardiff, and
M B Gardner
January 1951,
Acta - Unio Internationalis Contra Cancrum,
L J Faulkin, and
D J Mitchell, and
L J Young, and
D W Morris, and
R W Malone, and
R D Cardiff, and
M B Gardner
September 2005,
Veterinary pathology,
L J Faulkin, and
D J Mitchell, and
L J Young, and
D W Morris, and
R W Malone, and
R D Cardiff, and
M B Gardner
November 1979,
Journal of virology,
